Clerc Melitine, Belfeki Nabil, Gendrin Vincent, Klopfenstein Timothée, Ben Abdallah Yousri, Zayet Souheil
Department of Infectious Diseases, Nord Franche-Comté Hospital, 90400, Trévenans, France.
Department of Internal Medicine. Groupe Hospitalier Sud Ile de France, 77000, Melun, France.
Urol Case Rep. 2021 Nov 17;40:101949. doi: 10.1016/j.eucr.2021.101949. eCollection 2022 Jan.
Granulomatosis with polyangiitis (GPA) is an antineutrophil cytoplasmic antibody (ANCA) associated; vasculitis affecting small vessels and mainly cause upper and lower respiratory tract and renal involvement. Urogenital involvement is extremely rare and poorly described in the literature. We report herein a case of a 46-year old immunocompetent patient presenting with recurrent urinary tract infections and bladder retention with incidental findings of sinusitis, and pulmonary mass revealing GPA.
肉芽肿性多血管炎(GPA)是一种与抗中性粒细胞胞浆抗体(ANCA)相关的血管炎,累及小血管,主要导致上、下呼吸道及肾脏受累。泌尿生殖系统受累极为罕见,文献中对此描述甚少。我们在此报告一例46岁免疫功能正常的患者,该患者反复出现尿路感染和膀胱潴留,偶然发现鼻窦炎和肺部肿块,最终诊断为GPA。