Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil, 4365, 21040-360 Rio de Janeiro, RJ, Brazil.
Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Higiene Veterinária e Saúde Pública, Rua Professor Doutor Walter Mauricio Correa, s/n, 18618-681 Botucatu, SP, Brazil.
An Acad Bras Cienc. 2021 Dec 1;93(suppl 4):e20201682. doi: 10.1590/0001-3765202120201682. eCollection 2021.
In canine visceral leishmaniasis, coinfections can aggravate the disease. Our aim was to investigate Brucella canis in dogs infected with Leishmania infantum. One hundred and six L. infantum-seropositive dogs were submitted to serology for B. canis, PCR for B. canis and L. infantum, and histopathological analysis of the genital tract. Anti-B. canis antibodies were detected in seven dogs whose clinical signs, L. infantum load and histological alterations were similar to those of seronegative animals. The circulation of anti-B. canis antibodies was low but demonstrates the exposure of dogs to this bacterium in a visceral leishmaniasis-endemic area.
在犬内脏利什曼病中，合并感染会加重病情。我们的目的是研究感染利什曼原虫的犬中的犬种布鲁氏菌。对 106 只利什曼原虫血清阳性的犬进行了犬种布鲁氏菌血清学检测、PCR 检测和生殖道组织病理学分析。7 只犬检测出抗犬种布鲁氏菌抗体，其临床症状、利什曼原虫负荷和组织学改变与血清阴性动物相似。抗犬种布鲁氏菌抗体的循环水平较低，但表明在利什曼病流行地区，这些犬接触到了这种细菌。
