Senac M O, Isaacs H, Gwinn J L
Radiology. 1986 Aug;160(2):491-5. doi: 10.1148/radiology.160.2.3487812.
Primary bone tumors in early childhood are uncommon, and the incidence of malignancy in the 1st decade of life has not been evaluated adequately in the literature. For this reason, we conducted a retrospective review of 268 biopsies of the bone in 249 patients who were less than 10 years of age. Benign tumors were found much more frequently than malignant lesions. Osteochondroma and histiocytosis X were the most common lesions. The incidence of several benign lesions in our series was deceptively low, as many lesions showed typical radiographic findings, precluding the need for biopsy or excision. Of 41 primary malignant bone tumors, Ewing sarcoma was slightly more common than osteosarcoma. The rib was the most frequent site of the former; the distal femur, of the latter.
儿童期原发性骨肿瘤并不常见，且文献中对10岁前儿童恶性骨肿瘤的发病率评估不足。因此，我们对249例10岁以下儿童的268份骨活检进行了回顾性研究。发现良性肿瘤比恶性病变更为常见。骨软骨瘤和组织细胞增多症X是最常见的病变。在我们的系列研究中，一些良性病变的发病率看似较低，因为许多病变具有典型的影像学表现，无需活检或切除。在41例原发性恶性骨肿瘤中，尤因肉瘤比骨肉瘤略常见。前者最常见于肋骨；后者最常见于股骨远端。
