Magnusson M, Pyykkö I, Norrving B
Acta Otolaryngol. 1986 May-Jun;101(5-6):361-70. doi: 10.3109/00016488609108620.
The relationship of mean velocity of optokinetic nystagmus (OKN) to pursuit eye movements (PEM), to vestibular nystagmus and to voluntary saccades was analysed in 10 patients with peripheral vestibular lesions and in 30 patients with central vestibular lesions. PEM and vestibular nystagmus were significantly correlated to OKN, suggesting that a common neural pathway is used in the generation of these eye movements. Weak or no correlation was found between saccadic peak velocity and slow phase velocity of OKN. Using multiple linear regression analysis, it was found that 78.5% of the variation in the slow-phase velocity of OKN could be explained by a synthesis of PEM and vestibular test data. PEM test data were more powerful than those of vestibular nystagmus in deduction of OKN. The possible appearance of slow build-up of OKN could not be deduced from the reduction of PEM. Hence, the relationship between PEM and OKN in man is not a simple linear one, but is more complex.
分析了10例外周性前庭病变患者和30例中枢性前庭病变患者的视动性眼震（OKN）平均速度与追踪性眼球运动（PEM）、前庭性眼震及随意性扫视之间的关系。PEM和前庭性眼震与OKN显著相关，提示这些眼球运动的产生使用了共同的神经通路。在扫视峰值速度与OKN慢相速度之间发现弱相关或无相关性。使用多元线性回归分析发现，OKN慢相速度变化的78.5%可由PEM和前庭测试数据的综合来解释。在推断OKN方面，PEM测试数据比前庭性眼震的数据更具说服力。无法从PEM的降低推断出OKN可能出现的缓慢增强情况。因此，人类中PEM与OKN之间的关系不是简单的线性关系，而是更复杂的关系。
