Jennifer M. Livermore is Advanced Practice Registered Nurse in Infectious Disease, CHI St Elizabeth, 555 South 70th St, Lincoln, NE 68506 (
AACN Adv Crit Care. 2021 Dec 15;32(4):398-403. doi: 10.4037/aacnacc2021226.
The first confirmed case of COVID-19 in the United States was reported on January 20, 2020. Most infected individuals experience a mild illness with loss of taste and smell, body aches, fatigue, cough, and fever. However, about 5% of patients become critically ill and experience more serious symptoms such as respiratory distress, pulmonary emboli, or even multisystem organ failure. Those who become critically ill with COVID-19 are at high risk for superinfections, including pulmonary, bloodstream, and urinary tract infections. Invasive aspergillosis is emerging as a serious secondary pulmonary infection in patients with COVID-19 who experience respiratory distress syndrome. If these patients are not accurately diagnosed and subsequently treated, the infection can be fatal. This case study describes COVID-19-associated pulmonary aspergillosis in the critically ill patient.
美国首例新冠肺炎确诊病例报告于 2020 年 1 月 20 日。大多数受感染个体表现为轻症，伴有味觉和嗅觉丧失、身体疼痛、乏力、咳嗽和发热。然而，约 5%的患者病情恶化，出现更严重的症状，如呼吸窘迫、肺栓塞，甚至多器官功能衰竭。新冠肺炎重症患者极易发生继发感染，包括肺部、血液和尿路感染。侵袭性曲霉菌病正在成为呼吸窘迫综合征新冠肺炎患者严重的继发性肺部感染。如果这些患者未得到准确诊断和及时治疗，感染可能致命。本病例研究描述了一名重症新冠肺炎患者合并肺曲霉菌病。
