Department of Surgrey, 4157Conemaugh Health System, Johnstown, PA, USA.
Department of Surgrey, 21654UConn Health, Farmington, CT, USA.
Am Surg. 2022 Apr;88(4):653-657. doi: 10.1177/00031348211058639. Epub 2021 Dec 8.
Health care-associated pneumonias (HAPs) are a significant comorbidity seen in hospitalized patients. Traumatic injury is a known independent risk factor for the development of HAP. Trauma-related injuries also contribute to an increase in the rate of pneumonia in mechanically ventilated patients requiring intensive care unit (ICU) treatment. In 2011, the ventilator-associated pneumonia (VAP) rate among ICU patients at our institution (CMMC) increased dramatically. As a result, our infection control specialists performed a focused review of these patients and found a likely association between these infections and patients requiring pre-hospital intubation. Their determination prompted a July 2012 revision of the CMMC Trauma/Surgery Admission ICU protocol for ventilated patients to include bronchoscopy for patients who have been intubated pre-hospital providing no contraindications were present. Our aim was to ascertain any influence of the protocol change on the rate of VAP. We conducted a retrospective medical record review of trauma patients who were intubated in the field or ED and seen at our institution (an accredited Level 1 trauma center) from 2012 to 2018. Applying the current definition of VAP from the Centers for Disease Control and Prevention (CDC) to data collected from the CMMC trauma registry, we observed a 13% lower VAP rate in the bronchoscopy group () as compared to the group that did not receive bronchoscopy () ( < .025). Based on our results, we determined that bronchoscopy performed in this setting does support a statistically significant decrease in the rate of ventilator-associated pneumonia.
医院获得性肺炎(HAPs)是住院患者中常见的严重合并症。创伤是 HAP 发生的已知独立危险因素。创伤相关损伤也会增加需要重症监护病房(ICU)治疗的机械通气患者肺炎的发生率。2011 年,我们机构(CMMC)的 ICU 患者呼吸机相关性肺炎(VAP)的发生率急剧上升。因此,我们的感染控制专家对这些患者进行了重点审查,发现这些感染与需要院前插管的患者之间可能存在关联。他们的结论促使 CMMC 创伤/外科入院 ICU 协议在 2012 年 7 月进行修订,规定对院前插管的患者进行支气管镜检查,只要没有禁忌症。我们的目的是确定该协议变更对 VAP 发生率的任何影响。我们对 2012 年至 2018 年在我们机构(经认可的一级创伤中心)接受过院前插管的创伤患者进行了回顾性病历审查。我们将疾病预防控制中心(CDC)提出的 VAP 现行定义应用于从 CMMC 创伤登记处收集的数据,观察到支气管镜组的 VAP 发生率降低了 13%( ),而未接受支气管镜检查的组( )( <.025)。根据我们的结果,我们确定在这种情况下进行支气管镜检查确实支持呼吸机相关性肺炎发生率的统计学显著降低。