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新型腹腔镜手术修复剖宫产瘢痕缺陷,无需处理瘢痕切除。

Novel laparoscopic surgery for the repair of cesarean scar defect without processing scar resection.

机构信息

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.

出版信息

BMC Pregnancy Childbirth. 2021 Dec 8;21(1):815. doi: 10.1186/s12884-021-04281-8.

Abstract

BACKGROUND

Cesarean scar defect (CSD), especially CSD with residual myometrium less than 3 mm is reported to be the highest risk agent associated with uterine rupture for subsequent pregnancy. Currently, laparoscopic resection and suture was the mainstay therapy method for CSD with a residual myometrium less than 3 mm in women with a desire to conceive. Besides, the women have CSD related symptoms, especially postmenstrual bleeding, should be recommended for CSD treatment. This study is to investigate the efficiency of this novel laparoscopic surgery for the repair of cesarean scar defect (CSD) without scar resection for residual myometrium thickening.

METHOD

This retrospective clinical study enrolled 76 women diagnosed with CSD who had a residual myometrium thickness less than 3 mm and also had a desire to conceive, had undergone laparoscopic surgery for the repair of CSD in the time period March 2016 to March 2018. Two study cohorts were created among the 76 patients: 40 patients had undergone the novel laparoscopic repair of CSD without processing scar resection (Group A), whereas 36 patients had undergone the traditional laparoscopic resection and suture of CSD (Group B).

RESULTS

Residual myometrium thickening occurred among all the 76 patients and the average residual myometrium thickness was increased to almost 6 mm, presenting no between-group difference. In Group A, all the CSD-related postmenstrual bleeding was resolved or improved, but one patient in Group B has no obvious change to postmenstrual bleeding. After CSD repair, 20 patients got pregnant naturally in Group A, and there was no cesarean scar pregnancy and uterine rupture. While, there were 9 cases of natural pregnancy in Group B. No uterine rupture occurred among these 9 pregnant women of Group B, but 1 case of pregnancy was terminated due to cesarean scar pregnancy.

CONCLUSION

Laparoscopic repair without processing scar resection seems to be a feasible, safe and simple operative approach for CSD treatment, which can thicken residual myometrium and improve postmenstrual bleeding.

摘要

背景

剖宫产术后子宫瘢痕缺陷(CSD),尤其是残余肌层厚度<3mm 的 CSD,被认为是与再次妊娠相关子宫破裂的最高风险因素。目前,对于有生育要求且残余肌层厚度<3mm 的 CSD 患者,腹腔镜下切除缝合是主要的治疗方法。此外,对于有 CSD 相关症状,尤其是月经过多的患者,建议进行 CSD 治疗。本研究旨在探讨一种新型的腹腔镜手术方法治疗残余肌层厚度无明显变薄的 CSD。

方法

本回顾性临床研究纳入了 2016 年 3 月至 2018 年 3 月期间因 CSD 且残余肌层厚度<3mm 且有生育要求而行腹腔镜 CSD 修补术的 76 例患者。根据手术方式的不同,将 76 例患者分为两组:40 例行新型腹腔镜 CSD 修补术(无瘢痕切除)(A 组),36 例行传统腹腔镜下切除缝合术(B 组)。

结果

76 例患者的残余肌层均增厚,平均残余肌层厚度增加至近 6mm,两组间差异无统计学意义。A 组患者的 CSD 相关月经过多均得到缓解或改善,但 B 组患者中 1 例月经过多无明显改善。CSD 修补术后,A 组有 20 例患者自然受孕,无 CSD 妊娠和子宫破裂。B 组有 9 例自然受孕,无子宫破裂,其中 1 例因 CSD 妊娠终止妊娠。

结论

腹腔镜下不处理瘢痕切除治疗 CSD 是一种可行、安全、简单的手术方法,可以增厚残余肌层,改善月经过多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c5/8653604/c62d05054ed9/12884_2021_4281_Fig1_HTML.jpg

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