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再生障碍性贫血继发颅内高压:一例报告及当前概念综述

Secondary intracranial hypertension in aplastic anemia: A case report and review of current concepts.

作者信息

Al-Musalami Adil, Elmanzalawy Alaa, Wali Yasser, Ganesh Anuradha

机构信息

Ophthalmology Program, Oman Medical Specialty Board, Muscat, Oman.

Department of Radiology, Sultan Qaboos University Hospital, Muscat, Oman.

出版信息

Oman J Ophthalmol. 2021 Oct 20;14(3):190-195. doi: 10.4103/ojo.ojo_79_21. eCollection 2021 Sep-Dec.

Abstract

Intracranial hypertension (IH) when detected mandates prompt and appropriate therapy to avoid permanent visual impairment. We report a 7-year-old boy who presented to the emergency services with purpuric rashes and bruises. Peripheral blood smear and bone marrow aspiration confirmed the diagnosis of aplastic anemia. During admission, the child developed headache, nausea, vomiting, and diplopia. Ophthalmic examination revealed intermittent esotropia and bilateral papilledema. The findings on neuroimaging and lumbar puncture led to the diagnosis of secondary IH (SIH). The intracranial pressure normalized on treatment with oral acetazolamide, oral furosemide, and intravenous dexamethasone.

摘要

颅内高压(IH)一旦被检测到,就需要立即进行适当治疗,以避免永久性视力损害。我们报告一名7岁男孩,他因紫癜皮疹和瘀伤被送往急诊。外周血涂片和骨髓穿刺确诊为再生障碍性贫血。住院期间,该患儿出现头痛、恶心、呕吐和复视。眼科检查发现间歇性内斜视和双侧视乳头水肿。神经影像学和腰椎穿刺检查结果导致继发性颅内高压(SIH)的诊断。口服乙酰唑胺、口服呋塞米和静脉注射地塞米松治疗后颅内压恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/796f/8597811/e07b7e9b6caf/OJO-14-190-g001.jpg

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