Zhang Siyi, Yan Yan, Lu Yang, Zhou Yixiong, Fu Yao
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China.
Front Med (Lausanne). 2021 Nov 22;8:732041. doi: 10.3389/fmed.2021.732041. eCollection 2021.
This study aimed to investigate the effect of transcutaneous upper eyelid blepharoplasty on lipid layer thickness (LLT) and blink parameters in young women during the early postoperative period. This prospective study included 110 eyes of 55 young female patients (age range, 19-31 years) who underwent transcutaneous upper eyelid blepharoplasty. The LLT and blink parameters measured using a LipiView interferometer were recorded before the surgery and 1 week and 1 month after the surgery. Ocular Surface Disease Index (OSDI) score, noninvasive tear film breakup time (NITBUT), and palpebral fissure height (PFH) measurements were also performed at each time point. The number of blinks significantly decreased ( < 0.001), and the number of partial blinks and partial blink rate (PBR) significantly increased 1 week after the surgery ( = 0.002 and < 0.001); they all returned to baseline in 1 month. The LLT and OSDI score increased significantly 1 week and 1 month after the surgery ( < 0.001 and < 0.001). A significant increase in the NITBUT and a significant decrease in the PFH were observed 1 week after the surgery ( < 0.001 and < 0.001), and the values returned to baseline 1 month after the surgery. No clinical correlation was found between blink parameters and ocular surface parameters. Transcutaneous upper eyelid blepharoplasty led to a change in blink parameters and ocular surface parameters during the early postoperative period. However, this influence was temporary, and the transitory change in blink parameters had no effects on the ocular surface environment.
本研究旨在调查经皮上睑成形术对年轻女性术后早期脂质层厚度(LLT)和眨眼参数的影响。这项前瞻性研究纳入了55例接受经皮上睑成形术的年轻女性患者(年龄范围19 - 31岁)的110只眼睛。使用LipiView干涉仪测量的LLT和眨眼参数在手术前、术后1周和1个月进行记录。在每个时间点还进行眼表疾病指数(OSDI)评分、无创泪膜破裂时间(NITBUT)和睑裂高度(PFH)测量。术后1周眨眼次数显著减少(<0.001),部分眨眼次数和部分眨眼率(PBR)显著增加(=0.002和<0.001);1个月后均恢复至基线水平。术后1周和1个月LLT和OSDI评分显著增加(<0.001和<0.001)。术后1周观察到NITBUT显著增加,PFH显著降低(<0.001和<0.001),术后1个月这些值恢复至基线水平。眨眼参数与眼表参数之间未发现临床相关性。经皮上睑成形术在术后早期导致眨眼参数和眼表参数发生变化。然而,这种影响是暂时的,眨眼参数的短暂变化对眼表环境没有影响。