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非重症监护病房麻醉后成年患者术后谵妄筛查工具:系统评价与荟萃分析

Postoperative delirium screening tools for post-anaesthetic adult patients in non-intensive care units: A systematic review and meta-analysis.

作者信息

Kim Sujeong, Choi Eunju, Jung Youngsun, Jang Insil

机构信息

Department of Nursing, Asan Medical Center, Seoul, Korea.

Department of Nursing, Chung-Ang University, Seoul, Korea.

出版信息

J Clin Nurs. 2023 May;32(9-10):1691-1704. doi: 10.1111/jocn.16157. Epub 2021 Dec 8.

Abstract

AIMS AND OBJECTIVES

To identify the most accurate postoperative delirium screening tools for detecting postoperative delirium among patients who underwent general anaesthesia surgery in general wards.

BACKGROUND

The lack of detection of postoperative delirium can negatively affect the patient's condition, along with their postoperative treatment and rehabilitation, and it can prolong their hospitalisation, persists cognitive dysfunction and increases mortality. Screening for postoperative delirium in hospitalised patients as nursing assessment is routine clinical practice for early detection.

DESIGN

A systematic review and meta-analysis.

METHODS

MEDLINE, Embase, CINAHL, KoreaMed and Cochrane electronic databases were searched using the key words delirium, postoperative, assessment or screening, and adult for articles published up to April 2020, with no limit on the year of publishing. Only prospective cohort studies reporting sensitivity and specificity values were included. We followed the recommendations of the Cochrane Handbook of Diagnostic Test Accuracy Reviews and the PRISMA checklist. The Quality Assessment of the Diagnostic Accuracy Studies-2 tool was used for data extraction and quality assessment, while a bivariate random-effects meta-analysis model was used for pooling and comparing diagnostic accuracy and providing a summary of evidence.

RESULTS

Six delirium assessment tools were evaluated from nine papers including 3088 patients. Due to the limited number of papers, the meta-analysis included the Confusion Assessment Method (CAM) and its variants, Delirium Detection Score (DDS) and Nurses' Delirium Screening Checklist (NuDESC). Overall, NuDESC demonstrated higher sensitivity than CAM or DDS, while all showed high specificity (0.90 or greater).

CONCLUSION

This review suggested that NuDESC can be employed as an accurate screening tool with high specificity for assessing postoperative delirium during routine checkups. However, it is necessary to consider suitable cut-off values, which is the reference point, in accordance with the clinical setting and the patients' condition.

RELEVANCE TO CLINICAL PRACTICE

NuDESC reported the best evidence of diagnostic accuracy, and we recommend clinical nurses to employ this easy-to-use and validated tool for daily screening of postoperative delirium in general wards to facilitate its early detection and the accurate estimation of its prevalence.

摘要

目的

确定在普通病房接受全身麻醉手术患者中检测术后谵妄的最准确的术后谵妄筛查工具。

背景

术后谵妄检测的缺乏会对患者病情、术后治疗及康复产生负面影响,延长住院时间,导致持续的认知功能障碍并增加死亡率。在住院患者中筛查术后谵妄是护理评估的常规临床实践,以便早期发现。

设计

系统评价和荟萃分析。

方法

使用关键词谵妄、术后、评估或筛查以及成人检索MEDLINE、Embase、CINAHL、KoreaMed和Cochrane电子数据库,检索截至2020年4月发表的文章,对发表年份无限制。仅纳入报告敏感性和特异性值的前瞻性队列研究。我们遵循了Cochrane诊断试验准确性评价手册和PRISMA清单的建议。使用诊断准确性研究质量评估-2工具进行数据提取和质量评估,同时使用双变量随机效应荟萃分析模型汇总和比较诊断准确性并提供证据总结。

结果

从9篇论文中评估了6种谵妄评估工具,包括3088例患者。由于论文数量有限,荟萃分析纳入了意识错乱评估法(CAM)及其变体、谵妄检测评分(DDS)和护士谵妄筛查清单(NuDESC)。总体而言,NuDESC表现出比CAM或DDS更高的敏感性,而所有工具均显示出高特异性(0.90或更高)。

结论

本综述表明,NuDESC可作为一种准确的筛查工具,在常规检查中评估术后谵妄时具有高特异性。然而,有必要根据临床情况和患者病情考虑合适的截断值,截断值是参考点。

与临床实践的相关性

NuDESC报告了诊断准确性的最佳证据,我们建议临床护士使用这种易于使用且经过验证的工具在普通病房日常筛查术后谵妄,以促进早期发现并准确估计其患病率。

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