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524 例骨水泥型和非骨水泥型内侧单髁膝关节置换术后 5 年临床结果比较。

Comparison of five-year clinical outcomes of 524 cemented and cementless medial unicompartmental knee replacements.

机构信息

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.

Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.

出版信息

Knee. 2022 Jan;34:89-97. doi: 10.1016/j.knee.2021.08.015. Epub 2021 Dec 6.

Abstract

AIM

To compare the outcomes of cemented and cementless Unicompartmental Knee Replacements (UKR) at 5 years after surgery.

METHODS

262 cemented and 262 cementless medial mobile-bearing UKR, implanted by four high-volume surgeons using identical indications and surgical techniques, were reviewed by independent physiotherapists at 5 years. Survival, Oxford Knee Score (OKS), American Knee Society Score (AKSS), and EQ-5D-5L were assessed. The cementless cohort was mainly implanted after the cemented. Each cohort was divided into early and late sub-groups and compared, to assess if any differences were due to progressive improvement in surgical practice over time.

RESULTS

There were no significant differences between the cohorts for demographics, pre-operative scores, and 5-year revision (0.8%), re-operation (1.5%), and complication rates (5%). The cementless cohort had significantly better 5-year OKS (43v41, p = 0.008), AKSS-Objective (94v90, p = 0.049) and EQ-5D-5L (0.81v0.87, p = 0.0001). Pain sub-scores within OKS, AKSS, and EQ-5D-5L were also significantly better in the cementless cohort, and the differences were proportionally much greater and more significant than differences in their respective overall scores. There was no significant improvement in scores between the early and late subgroups of the cohorts, whereas the 'early-cementless' cohort had significantly better scores than the contemporaneously implanted 'late-cemented' cohort. This suggests that differences found were due to implant type, instead of improved surgical practice over time.

CONCLUSION

Cementless UKR is associated with better clinical outcomes than cemented UKR, which is primarily due to improved pain relief. Both cemented and cementless UKR are safe with low reoperation and complication rates, and a 5-year survival of 99%.

摘要

目的

比较骨水泥型和非骨水泥型单髁膝关节置换术后 5 年的结果。

方法

由四位高年资医生采用相同的适应证和手术技术,分别对 262 例骨水泥型和 262 例非骨水泥型内侧单动式活动平台膝关节置换术患者进行随访,随访时间为 5 年。采用独立的理疗师评估患者的生存率、牛津膝关节评分(OKS)、美国膝关节协会评分(AKSS)和 EQ-5D-5L。非骨水泥组主要在骨水泥组之后植入。将每个队列分为早期和晚期亚组进行比较,以评估任何差异是否由于手术实践随时间的推移而逐渐改善。

结果

两组患者的人口统计学资料、术前评分和 5 年翻修率(0.8%)、再手术率(1.5%)和并发症发生率(5%)无显著差异。非骨水泥组患者的 5 年 OKS(43 分比 41 分,p=0.008)、AKSS-客观评分(94 分比 90 分,p=0.049)和 EQ-5D-5L(0.81 分比 0.87 分,p=0.0001)显著更好。OKS、AKSS 和 EQ-5D-5L 的疼痛评分也显著更好,差异的比例明显大于且明显高于各自的总分差异。两组患者的早期和晚期亚组之间的评分均无显著改善,而“早期非骨水泥组”的评分明显优于同期植入的“晚期骨水泥组”。这表明发现的差异主要是由于植入物类型不同,而不是随时间推移手术实践的改善。

结论

非骨水泥型单髁膝关节置换术的临床结果优于骨水泥型单髁膝关节置换术,这主要是由于疼痛缓解更好。骨水泥型和非骨水泥型单髁膝关节置换术均安全,再手术率和并发症发生率低,5 年生存率为 99%。

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