影响视网膜中央静脉阻塞患者初诊时视力的背景因素：日本多中心研究
Background Factors Affecting Visual Acuity at Initial Visit in Eyes with Central Retinal Vein Occlusion: Multicenter Study in Japan.
作者信息
Kondo Mineo, Noma Hidetaka, Shimura Masahiko, Sugimoto Masahiko, Matsui Yoshitsugu, Kato Kumiko, Saishin Yoshitsugu, Ohji Masahito, Ishikawa Hiroto, Gomi Fumi, Iwata Kensaku, Yoshida Shigeo, Kusuhara Sentaro, Hirai Hiromasa, Ogata Nahoko, Hirano Takao, Murata Toshinori, Tsuboi Kotaro, Kamei Motohiro, Kinoshita Takamasa, Kuwayama Soichiro, Hirano Yoshio, Ohta Manami, Kimura Kazuhiro, Takayama Kei, Takeuchi Masaru, Takamura Yoshihiro, Okamoto Fumiki, Mitamura Yoshinori, Terasaki Hiroto, Sakamoto Taiji, Group On Behalf Of Japan Clinical Retina Study J-Crest
机构信息
Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Department of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Hachioji 193-0998, Japan.
出版信息
J Clin Med. 2021 Nov 29;10(23):5619. doi: 10.3390/jcm10235619.
PURPOSE
To determine the baseline characteristics of patients with central retinal vein occlusion (CRVO) that were significantly associated with the best-corrected visual acuity (BCVA) at the initial examination.
METHODS
This was a retrospective multicenter study using the medical records registered in 17 ophthalmological institutions in Japan. Patients with untreated CRVO (≥20-years-of-age) who were initially examined between January 2013 and December 2017 were studied. The patients' baseline factors that were significantly associated with the BCVA at the initial examination were determined by univariate and multivariate linear regression analyses.
RESULTS
Data from 517 eyes of 517 patients were analyzed. Univariate analyses showed that an older age ( = 0.194, < 0.001) and the right eye ( = -0.103, < 0.019) were significantly associated with poorer BCVA at the initial visit. Multivariate analyses also showed that an older age ( = 0.191, < 0.001) and the right eye ( = -0.089, = 0.041) were significantly associated with poorer BCVA at the initial visit.
CONCLUSIONS
The results indicate that an older age, a known strong factor, and the right eye were significantly associated with poorer BCVA at the initial visit to the hospital. These results suggest that functional and/or anatomical differences between the right and left eyes may be involved in these results.
目的
确定视网膜中央静脉阻塞（CRVO）患者的基线特征，这些特征与初次检查时的最佳矫正视力（BCVA）显著相关。
方法
这是一项回顾性多中心研究，使用了日本17家眼科机构登记的病历。对2013年1月至2017年12月期间初次检查的未经治疗的CRVO患者（≥20岁）进行研究。通过单因素和多因素线性回归分析确定与初次检查时BCVA显著相关的患者基线因素。
结果
分析了517例患者的517只眼的数据。单因素分析显示，年龄较大（=0.194，<0.001）和右眼（=-0.103，<0.019）与初次就诊时较差的BCVA显著相关。多因素分析还显示，年龄较大（=0.191，<0.001）和右眼（=-0.089，=0.041）与初次就诊时较差的BCVA显著相关。
结论
结果表明，年龄较大（一个已知的重要因素）和右眼与初次就诊时较差的BCVA显著相关。这些结果表明，左右眼之间的功能和/或解剖差异可能与这些结果有关。
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