钠钙磷氧氮化物的体外溶出度
In Vitro Dissolution of Na-Ca-P-Oxynitrides.
作者信息
Wójcik Natalia Anna, Sinitsyna Polina, Ali Sharafat, Hupa Leena, Jonson Bo
机构信息
Advanced Materials Center, Institute of Nanotechnology and Materials Engineering, Gdańsk University of Technology, 11/12 G. Narutowicza Street, 80-233 Gdańsk, Poland.
Department of Built Environment and Energy Technology, Linnaeus University, 35195 Växjö, Sweden.
出版信息
Materials (Basel). 2021 Dec 3;14(23):7425. doi: 10.3390/ma14237425.
Sodium-calcium-phosphate based oxynitride glasses and glass-ceramics doped with Mg, Si, and Nb were studied in vitro in simulated body fluid (SBF) under static conditions. The release of ions and pH changes up to 7 days of immersion were investigated. The nitrogen incorporation into phosphate glass matrix was found to notably influence in vitro dissolution only of homogenous glasses. Increasing the nitrogen content in the samples decreased the mean mass loss, while the niobate incorporation increased it. The correlation between the nitrogen content and increase in pH of SBF was also observed. The presence of phosphates crystallites was found to support the dissolution process at the beginning step (up to 3 days).
研究了掺杂Mg、Si和Nb的钠钙磷基氮氧化物玻璃及玻璃陶瓷在静态条件下于模拟体液（SBF）中的体外性能。研究了浸泡7天内的离子释放和pH变化。发现氮掺入磷酸盐玻璃基体仅对均质玻璃的体外溶解有显著影响。样品中氮含量的增加降低了平均质量损失，而铌酸盐的掺入则增加了平均质量损失。还观察到氮含量与SBF的pH升高之间的相关性。发现磷酸盐微晶的存在在初始阶段（长达3天）促进了溶解过程。
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