Institute for Physical Activity and Nutrition, Deakin University, Burwood, VIC 3125, Australia.
School of Health, Federation University Australia, Berwick, VIC 3806, Australia.
Int J Environ Res Public Health. 2021 Nov 23;18(23):12277. doi: 10.3390/ijerph182312277.
Diabetes and chronic kidney disease (CKD) are a major public health burden in low- and middle-income countries. This study aimed to explore factors associated with CKD in patients with type 2 diabetes (T2D) in Bangladesh. A cross-sectional study was conducted among 315 adults with T2D presenting at the outpatient department of Bangladesh Institute of Health Sciences (BIHS) hospital between July 2013 to December 2013. CKD was diagnosed based on the estimated glomerular filtration rate using the 'Modification of Diet in Renal Disease' equations and the presence of albuminuria estimated by the albumin-to-creatinine ratio. Multivariate logistic regression analysis was used to determine the factors associated with CKD. The overall prevalence of CKD among patients with T2D was 21.3%. In the unadjusted model, factors associated with CKD included age 40-49 years (OR: 5.7, 95% CI: 1.3-25.4), age 50-59 years (7.0, 1.6-39), age ≥60 years (7.6, 1.7-34), being female (2.2, 1.2-3.8), being hypertensive (1.9, 1.1-3.5), and household income between 10,001 and 20,000 Bangladeshi taka, BDT (2.9, 1.0-8.2) compared with income ≤10,000 BDT. However, after adjustment of other covariates, only the duration of hypertension and household income (10,001-20,000 BDT) remained statistically significant. There is a need to implement policies and programs for early detection and management of hypertension and CKD in T2D patients in Bangladesh.
糖尿病和慢性肾脏病(CKD)是中低收入国家的主要公共卫生负担。本研究旨在探讨孟加拉国 2 型糖尿病(T2D)患者 CKD 的相关因素。2013 年 7 月至 2013 年 12 月期间,在孟加拉国卫生科学研究所(BIHS)医院的门诊部门对 315 名成年 T2D 患者进行了横断面研究。CKD 的诊断基于使用“肾脏病饮食改良”方程估计的肾小球滤过率和白蛋白-肌酐比估计的白蛋白尿。采用多变量逻辑回归分析确定与 CKD 相关的因素。T2D 患者 CKD 的总体患病率为 21.3%。在未调整模型中,与 CKD 相关的因素包括 40-49 岁(OR:5.7,95%CI:1.3-25.4)、50-59 岁(7.0,1.6-39)、60 岁及以上(7.6,1.7-34)、女性(2.2,1.2-3.8)、高血压(1.9,1.1-3.5)和家庭收入在 10,001 至 20,000 塔卡之间(2.9,1.0-8.2)与收入≤10,000 塔卡相比。然而,在调整其他协变量后,只有高血压和家庭收入(10,001-20,000 塔卡)的持续时间仍然具有统计学意义。孟加拉国需要实施政策和计划,以早期发现和管理 T2D 患者的高血压和 CKD。