Clinical Medicine Department, Miguel Hernandez University, 03550 San Juan de Alicante, Spain.
Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, 46010 Valencia, Spain.
Int J Environ Res Public Health. 2021 Nov 25;18(23):12419. doi: 10.3390/ijerph182312419.
Evidence shows that objectives for detecting and controlling dyslipidemia are not being effectively met, and outcomes differ between men and women. This study aimed to assess gender-related differences in diagnostic inertia around dyslipidemia. This ambispective, epidemiological, cohort registry study included adults who presented to public primary health care centers in a Spanish region from 2008 to 2012, with dyslipidemia and without cardiovascular disease. Diagnostic inertia was defined as the registry of abnormal diagnostic parameters-but no diagnosis-on the person's health record in a window of six months from inclusion. A total of 58,970 patients were included (53.7% women) with a mean age of 58.4 years in women and 57.9 years in men. The 6358 (20.1%) women and 4312 (15.8%) men presenting diagnostic inertia had a similar profile, although in women the magnitude of the association with younger age was larger. Hypertension showed a larger association with diagnostic inertia in women than in men (prevalence ratio 1.81 vs. 1.56). The overall prevalence of diagnostic inertia in dyslipidemia is high, especially in women. Both men and women have a higher risk of cardiovascular morbidity and mortality.
证据表明,检测和控制血脂异常的目标并未得到有效实现,而且男性和女性的结果存在差异。本研究旨在评估血脂异常诊断惰性方面的性别差异。这项前瞻性、流行病学、队列登记研究纳入了 2008 年至 2012 年期间在西班牙某一地区的公立初级保健中心就诊的患有血脂异常且无心血管疾病的成年人。诊断惰性定义为在纳入后的六个月内,健康记录中登记了异常诊断参数但未做出诊断。共纳入 58970 名患者(53.7%为女性),女性的平均年龄为 58.4 岁,男性为 57.9 岁。6358 名(20.1%)女性和 4312 名(15.8%)男性出现诊断惰性,其特征相似,但女性中与年龄较小的关联程度更大。高血压在女性中的诊断惰性与男性相比更大(患病率比 1.81 比 1.56)。血脂异常的诊断惰性总体患病率较高,尤其是在女性中。男性和女性患心血管疾病发病率和死亡率的风险更高。