Kim Og Hyang, Lee Seung Won, Ha Eun Kyo, Kim Ju Hee, Jo Yun Hye, Rhie Seongyeong, Han Man Yong, Chae Kyu Young
Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Department of Data Science, Sejong University College of Software Convergence, Seoul, Korea.
Clin Exp Pediatr. 2022 Jun;65(6):312-319. doi: 10.3345/cep.2021.01417. Epub 2021 Dec 9.
Congenital muscular torticollis (CMT) is a common musculoskeletal disorder occurring at birth or in infancy.
This study aimed to investigate the risk of comorbidities in CMT and explore the differences in neurodevelopmental outcomes between children who received physical therapy and those who did not.
Children with CMT born in 2008 and 2009 in Korea were included. CMT was defined as a primary diagnosis of congenital deformity of sternocleidomastoid muscle according to the International Classification of Diseases 10th revision. Here we investigated the associated neurological/musculoskeletal comorbidities of children with CMT versus those of the general population. We divided those with torticollis into treatment and nontreatment groups and assessed their developmental outcomes within both groups of children using the Korean-Ages and Stages Questionnaire (K-ASQ).
Of the 917,707 children, 0.2% (n=1,719) were diagnosed with CMT. In children with torticollis, the prevalence of congenital hip deformities significantly increased to 4.5% (n=78). The prevalence of congenital head/spine deformities and other congenital malformations of the skull and facial bones increased to 2.6% (n=44), while the prevalence of congenital foot deformities was 2.4% (n=42). The risk ratio (RR) for delayed development based on the K-ASQ was higher for the total assessment (adjusted RR=0.97; 95% confidence interval, 0.93-0.99) in the CMT patients without physical therapy than in those with therapy. There was no significant intergroup difference in the assessment of each developmental area.
The prevalence of comorbid musculoskeletal deformities was higher in children with CMT than in the control group. The risk of developmental delay was higher in children who did not receive physical therapy than in those who did.
先天性肌性斜颈（CMT）是一种常见于出生时或婴儿期的肌肉骨骼疾病。
本研究旨在调查CMT患者合并症的风险，并探讨接受物理治疗的儿童与未接受物理治疗的儿童在神经发育结局方面的差异。
纳入2008年和2009年在韩国出生的CMT患儿。根据国际疾病分类第10版，CMT被定义为胸锁乳突肌先天性畸形的主要诊断。在此，我们调查了CMT患儿与普通人群相比相关的神经/肌肉骨骼合并症。我们将斜颈患儿分为治疗组和非治疗组，并使用韩国年龄和阶段问卷（K-ASQ）评估两组儿童的发育结局。
在917,707名儿童中，0.2%（n = 1,719）被诊断为CMT。在斜颈患儿中，先天性髋关节畸形的患病率显著增至4.5%（n = 78）。先天性头/脊柱畸形以及颅骨和面部骨骼的其他先天性畸形的患病率增至2.6%（n = 44），而先天性足部畸形的患病率为2.4%（n = 42）。基于K-ASQ的发育迟缓风险比（RR）在未接受物理治疗的CMT患者总评估中（调整RR = 0.97；95%置信区间，0.93 - 0.99）高于接受治疗的患者。在各个发育领域的评估中，组间无显著差异。
CMT患儿合并肌肉骨骼畸形的患病率高于对照组。未接受物理治疗的儿童发育迟缓风险高于接受治疗的儿童。
Zotero 插件
