Mameli O, Tolu E
Brain Res Bull. 1986 May;16(5):739-43. doi: 10.1016/0361-9230(86)90146-2.
Vestibular decompensation induced by spinal cord transection in left labyrinthectomized guinea pigs provoked asymmetrical excitability of the inferior olivary nuclei. In the right nucleus, spinal deafferentation induced a significantly increased response to electrical stimulation of the contralateral radial nerve and decreased response to ipsilateral radial nerve stimulation. In the left nucleus, opposite results were obtained. Increased responses were recorded in the I.O. neurons during electrical stimulation of the radial nerve ipsilateral to a previous hemilabyrinthectomy, and reduced responses during the electrical stimulation of the radial nerve of the opposite side. Since the inferior olive impinges on the vestibular nuclei both directly and indirectly through the cerebellar loop, it is possible that the inferior olive is involved in the spinal compensation of the vestibular deficits resulting from the hemilabyrinthectomy.
在左侧迷路切除的豚鼠中，脊髓横断诱导的前庭失代偿引发了下橄榄核的不对称兴奋性。在右侧核中，脊髓去传入导致对同侧桡神经电刺激的反应显著增加，而对同侧桡神经刺激的反应减少。在左侧核中，获得了相反的结果。在先前半侧迷路切除同侧的桡神经电刺激期间，下橄榄核神经元的反应增加，而在对侧桡神经电刺激期间反应减少。由于下橄榄核通过小脑环路直接和间接地影响前庭核，因此下橄榄核可能参与了半侧迷路切除导致的前庭缺陷的脊髓代偿。
