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升主动脉漂浮血栓相关的超急性同时性心脑梗死:一例报告

Hyperacute simultaneous cardiocerebral infarction related to floating thrombus in the ascending aorta: a case report.

作者信息

Issa Ranny, Gallissot Felix, Cochet Alexandre, Cottin Yves

机构信息

Department of Cardiology, University Teaching Hospital Burgundy, 14 rue Gaffarel, 21000, Dijon, France.

Department of Imagery, University Teaching Hospital Burgundy, 14 rue Gaffarel, 21000, Dijon, France.

出版信息

Eur Heart J Case Rep. 2021 Nov 8;5(12):ytab450. doi: 10.1093/ehjcr/ytab450. eCollection 2021 Dec.

Abstract

BACKGROUND

Ascending aortic thrombus has been reported in several case reports, often revealed by peripheral embolization, but very few revealed by cardiocerebral infarction. Moreover, there is no defined treatment strategy.

CASE SUMMARY

An 83-year-old woman was admitted to our intensive care unit for concurrent acute myocardial infarction (AMI) and acute stroke, both with the presence of an embolism. Imaging revealed a floating thrombus in the ascending aorta. The thrombus resolved after anticoagulant therapy was administered, and there was no subsequent embolism recurrence.

DISCUSSION

Floating thrombus in the ascending aorta is an unusual cause of AMI. The main mechanisms of thrombus formation include erosion of an atherosclerotic plaque, but it can also form without tissue abnormality with the probable implication of Virchow's triad. However, the precise mechanism for thrombogenesis remains unknown. In patients with a low surgical risk, we should consider surgical treatment, especially as anticoagulant therapy does not appear to reduce the risk of arterial embolization. Thrombolysis and endovascular interventions have also proven effective in certain cases. Overall, in patients with high surgical risk, decision will have to be made on a case-by-case basis.

KEYWORDS

Acute myocardial infarction • Embolic stroke • Coronary embolism • Ascending aorta thrombus • Floating thrombus • Case report.

摘要

背景

升主动脉血栓在一些病例报告中已有报道,通常由外周栓塞发现,但很少由心脑梗死发现。此外,尚无明确的治疗策略。

病例摘要

一名83岁女性因并发急性心肌梗死(AMI)和急性卒中入住我们的重症监护病房,两者均存在栓塞。影像学检查显示升主动脉内有一个漂浮血栓。给予抗凝治疗后血栓溶解,且随后无栓塞复发。

讨论

升主动脉内的漂浮血栓是AMI的一种不寻常病因。血栓形成的主要机制包括动脉粥样硬化斑块的侵蚀,但也可在无组织异常的情况下形成,可能与维勒布兰德三联征有关。然而,血栓形成的确切机制仍不清楚。对于手术风险低的患者,我们应考虑手术治疗,特别是因为抗凝治疗似乎并不能降低动脉栓塞的风险。溶栓和血管内介入治疗在某些病例中也已证明有效。总体而言,对于手术风险高的患者,必须逐案做出决策。

关键词

急性心肌梗死;栓塞性卒中;冠状动脉栓塞;升主动脉血栓;漂浮血栓;病例报告

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3631/8652107/11d4bcbd4a64/ytab450f1.jpg

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