Radhakrishnan K, Ashok P P, Sridharan R, Mousa M E
Neuroepidemiology. 1986;5(1):47-54. doi: 10.1159/000110812.
A total of 23 patients with motor neuron disease (MND), encompassing 17 cases of amyotrophic lateral sclerosis, 4 of progressive muscular atrophy and 2 of progressive bulbar palsy, was diagnosed in Benghazi, north-eastern Libya, between 1980 and 1985. The male to female ratio was 2.3:1. The average incidence of MND was 0.89/100,000 population/year (0.87 when age and sex-adjusted to the Libyan population). Eighteen patients were alive on the prevalence day, September 15, 1985, which provided a prevalence rate of 3.47/100,000 population (3.42 if adjusted). Age-specific incidence rates were highest in the 50- to 59-year-old age group, 8.14/100,000/year for men and 6.10/100,000/year for women. The median age at the time of diagnosis was 51 years, and the median duration for the 5 dead MND patients after the onset of the disease was 30 months. The median survival time for all MND cases combined was 42 months.
1980年至1985年期间，在利比亚东北部的班加西共诊断出23例运动神经元病（MND）患者，其中包括17例肌萎缩侧索硬化症、4例进行性肌肉萎缩症和2例进行性延髓麻痹。男女比例为2.3:1。MND的平均发病率为0.89/10万人口/年（根据利比亚人口的年龄和性别进行调整后为0.87）。在1985年9月15日患病率调查日，有18名患者存活，患病率为3.47/10万人口（调整后为3.42）。年龄别发病率在50至59岁年龄组最高，男性为8.14/10万/年，女性为6.10/10万/年。诊断时的中位年龄为51岁，5例死亡的MND患者发病后的中位病程为30个月。所有MND病例合并后的中位生存时间为42个月。
