Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:4213-4217. doi: 10.1109/EMBC46164.2021.9629950.
The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.
生物可吸收血管支架（BVS）的引入彻底改变了动脉粥样硬化的治疗方法。InSilc 是一个基于云环境的计算机临床试验（ISCT）平台，用于 BVS 的设计、开发和评估。该平台集成了先进的多学科和多尺度模型，以预测支架的短期/急性和中期/长期性能。在本研究中，InSilc 平台在一个用例场景中得到应用，展示了整个计算机模拟管道如何能够解释动脉解剖结构配置对支架植入的影响。
