Dobritsa V P, Sukhodoeva G S, Beklemishev N D
Zh Mikrobiol Epidemiol Immunobiol. 1986 Jun(6):59-62.
The sensitizing properties of different doses of the antigenic preparation obtained from H. influenzae by ultrasonic treatment have been studied. Small doses of the antigen have been found to induce immunoallergic transformations of type IV in sensitized guinea pigs. A considerable increase in the sensitizing dose of the antigen has been found to lead to the appearance of allergic reactions of type I. The regularities of the development of allergy to H. influenzae are discussed.
对通过超声处理从流感嗜血杆菌获得的不同剂量抗原制剂的致敏特性进行了研究。已发现小剂量抗原可诱导致敏豚鼠发生IV型免疫过敏转变。已发现抗原致敏剂量的显著增加会导致I型过敏反应的出现。文中讨论了对流感嗜血杆菌过敏发展的规律。