• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Prevalence of congenital heart disease among patients with down syndrome in Southwestern Saudi Arabia.沙特阿拉伯西南部唐氏综合征患者先天性心脏病的患病率。
Ann Afr Med. 2021 Oct-Dec;20(4):265-269. doi: 10.4103/aam.aam_57_20.
2
Congenital heart defects in Down syndrome patients from western Saudi Arabia.沙特阿拉伯西部唐氏综合征患者的先天性心脏缺陷
Saudi Med J. 2012 Nov;33(11):1211-5.
3
The spectrum of congenital heart diseases in down syndrome. A retrospective study from Northwest Saudi Arabia.唐氏综合征患者先天性心脏病的谱系：来自沙特阿拉伯西北部的一项回顾性研究。
Saudi Med J. 2016 Jul;37(7):767-72. doi: 10.15537/smj.2016.7.14536.
4
Survival analysis of Down syndrome with congenital heart disease: a 5-years registry at QSNICH.唐氏综合征合并先天性心脏病的生存分析：QSNICH的5年登记研究
J Med Assoc Thai. 2014 Jun;97 Suppl 6:S108-14.
5
Prevalence of congenital heart diseases in children with Down syndrome in Mansoura, Egypt: a retrospective descriptive study.埃及曼苏拉市唐氏综合征患儿先天性心脏病的患病率：一项回顾性描述性研究。
Ann Saudi Med. 2017 Sep-Oct;37(5):386-392. doi: 10.5144/0256-4947.2017.386.
6
Sex differences for major congenital heart defects in Down Syndrome: A population based study.唐氏综合征主要先天性心脏缺陷的性别差异：一项基于人群的研究。
Eur J Med Genet. 2018 Sep;61(9):546-550. doi: 10.1016/j.ejmg.2018.05.013. Epub 2018 May 9.
7
Prevalence of congenital heart defects associated with Down syndrome in Korea.韩国唐氏综合征相关先天性心脏缺陷的患病率。
J Korean Med Sci. 2014 Nov;29(11):1544-9. doi: 10.3346/jkms.2014.29.11.1544. Epub 2014 Nov 4.
8
Spectrum of congenital heart defects associated with Down Syndrome in high consanguineous Omani population.阿曼高近亲结婚人群中与唐氏综合征相关的先天性心脏缺陷谱。
Indian Pediatr. 2003 May;40(5):398-403.
9
Prevalence of congenital heart defects and persistent pulmonary hypertension of the neonate with Down syndrome.唐氏综合征新生儿先天性心脏病和持续性肺动脉高压的患病率。
Eur J Pediatr. 2010 Oct;169(10):1195-9. doi: 10.1007/s00431-010-1200-0. Epub 2010 Apr 23.
10
Maternal risk factors for congenital heart defects in infants with Down syndrome from Western Mexico.墨西哥西部地区唐氏综合征患儿先天性心脏病的母体危险因素
Am J Med Genet A. 2019 Sep;179(9):1857-1865. doi: 10.1002/ajmg.a.61300. Epub 2019 Jul 19.

引用本文的文献

1
Impact of Age and of the Patent Ductus Arteriosus on Pulmonary Hemodynamics in Children with Complete Atrioventricular Septal Defect.年龄及动脉导管未闭对完全性房室间隔缺损患儿肺血流动力学的影响
Pediatr Cardiol. 2024 Sep 2. doi: 10.1007/s00246-024-03636-0.
2
Analysis of Down syndrome newborn outcomes in three neonatal intensive care units in Rio de Janeiro, Brazil.巴西里约热内卢三家新生儿重症监护病房唐氏综合征新生儿结局分析
Rev Assoc Med Bras (1992). 2024 Apr 22;70(3):e20231186. doi: 10.1590/1806-9282.20231186. eCollection 2024.
3
Examining the Prevalence of Congenital Anomalies in Newborns: A Cross-Sectional Study at a Tertiary Care Maternity Hospital in Saudi Arabia.新生儿先天性异常患病率调查：沙特阿拉伯一家三级医疗妇产医院的横断面研究
Children (Basel). 2024 Feb 2;11(2):188. doi: 10.3390/children11020188.
4
Gender and its association with cardiac defects in down syndrome population at Children Hospital & Institute of Child Health, Lahore, Pakistan.巴基斯坦拉合尔儿童医院及儿童健康研究所唐氏综合征人群中的性别及其与心脏缺陷的关联。
Pak J Med Sci. 2024 Jan-Feb;40(3Part-II):371-375. doi: 10.12669/pjms.40.3.7346.
5
Prevalence and Pattern of Birth Defects in Saudi Arabia: A Systematic Review of Observational Studies.沙特阿拉伯出生缺陷的患病率及模式：观察性研究的系统评价
Pediatr Rep. 2023 Jul 20;15(3):431-441. doi: 10.3390/pediatric15030040.
6
Prevalence of Congenital Heart Defects in Individuals With Down Syndrome in Saudi Arabia: A Systematic Review and Meta-Analysis.沙特阿拉伯唐氏综合征患者先天性心脏病的患病率：一项系统评价和荟萃分析。
Cureus. 2022 Nov 18;14(11):e31638. doi: 10.7759/cureus.31638. eCollection 2022 Nov.

本文引用的文献

1
Down Syndrome.唐氏综合征
N Engl J Med. 2020 Jun 11;382(24):2344-2352. doi: 10.1056/NEJMra1706537.
2
Prevalence of congenital heart diseases in children with Down syndrome in Mansoura, Egypt: a retrospective descriptive study.埃及曼苏拉市唐氏综合征患儿先天性心脏病的患病率：一项回顾性描述性研究。
Ann Saudi Med. 2017 Sep-Oct;37(5):386-392. doi: 10.5144/0256-4947.2017.386.
3
Three-dimensional Echocardiography in Congenital Heart Disease: An Expert Consensus Document from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.先天性心脏病的三维超声心动图：欧洲心血管影像学会和美国超声心动图学会的专家共识文件
J Am Soc Echocardiogr. 2017 Jan;30(1):1-27. doi: 10.1016/j.echo.2016.08.022. Epub 2016 Nov 9.
4
Congenital heart disease and Down syndrome: various aspects of a confirmed association.先天性心脏病与唐氏综合征：已证实关联的多个方面
Cardiovasc J Afr. 2016 Sep/Oct;27(5):287-290. doi: 10.5830/CVJA-2016-019.
5
The spectrum of congenital heart diseases in down syndrome. A retrospective study from Northwest Saudi Arabia.唐氏综合征患者先天性心脏病的谱系：来自沙特阿拉伯西北部的一项回顾性研究。
Saudi Med J. 2016 Jul;37(7):767-72. doi: 10.15537/smj.2016.7.14536.
6
Trends in Congenital Heart Defects in Infants With Down Syndrome.唐氏综合征患儿先天性心脏病的变化趋势。
Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2016-0123. Epub 2016 Jun 1.
7
Down Syndrome: Changing Cardiac Phenotype?唐氏综合征：心脏表型会改变吗？
Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2016-1223. Epub 2016 Jun 1.
8
Associated congenital anomalies among cases with Down syndrome.唐氏综合征病例中的相关先天性异常。
Eur J Med Genet. 2015 Dec;58(12):674-80. doi: 10.1016/j.ejmg.2015.11.003. Epub 2015 Nov 11.
9
Prevalence of congenital heart defects associated with Down syndrome in Korea.韩国唐氏综合征相关先天性心脏缺陷的患病率。
J Korean Med Sci. 2014 Nov;29(11):1544-9. doi: 10.3346/jkms.2014.29.11.1544. Epub 2014 Nov 4.
10
Congenital heart defects in Down syndrome patients from western Saudi Arabia.沙特阿拉伯西部唐氏综合征患者的先天性心脏缺陷
Saudi Med J. 2012 Nov;33(11):1211-5.

沙特阿拉伯西南部唐氏综合征患者先天性心脏病的患病率。

Prevalence of congenital heart disease among patients with down syndrome in Southwestern Saudi Arabia.

机构信息

Department of Basic Medical Sciences, College of Medicine, University of Bisha, Bisha, Saudi Arabia.

Department of Family Medicine, College of Medicine, University of Bisha, Bisha, Saudi Arabia.

出版信息

Ann Afr Med. 2021 Oct-Dec;20(4):265-269. doi: 10.4103/aam.aam_57_20.

DOI:10.4103/aam.aam_57_20
PMID:34893563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8693744/
Abstract

BACKGROUND

There is a paucity of data on the prevalence and pattern of congenital heart disease (CHD) among patients with Down syndrome (DS) in Bisha, Saudi Arabia. The aim of the study was to determine the prevalence and patterns of CHD in patients with DS and explore the association of participants' sex with CHD in DS patients.

METHODOLOGY

A total of 42 patients with confirmed DS were enrolled in the study. Relevant data were obtained from the patients' records. The spectrum of CHD was analyzed and classified accordingly. Pearson's Chi-square was used to determine the association of gender with CHD.

RESULTS

Approximately 81% of the study participants had CHD. The most common CHD was atrial septal defect (28.5%), followed by ventricular septal defect (25%), patent ductus arteriosus (16%), and atrioventricular septal defect (14.3%). No significant association was found between CHDs and sex.

CONCLUSION

The prevalence of CHD in the study group was consistent with reports from other regions of Saudi Arabia and globally. Participants' sex was not associated with the occurrence of CHD in DS patients in this study.

摘要

背景

在沙特阿拉伯比沙，关于唐氏综合征（DS）患者先天性心脏病（CHD）的患病率和模式的数据很少。本研究的目的是确定 DS 患者中 CHD 的患病率和模式，并探讨参与者的性别与 DS 患者 CHD 的关系。

方法

共纳入 42 例确诊为 DS 的患者。从患者的病历中获取相关数据。分析 CHD 的谱并进行相应分类。采用 Pearson 卡方检验确定性别与 CHD 的关系。

结果

研究参与者中约有 81%患有 CHD。最常见的 CHD 是房间隔缺损（28.5%），其次是室间隔缺损（25%）、动脉导管未闭（16%）和房室间隔缺损（14.3%）。CHD 与性别之间无显著关联。

结论

研究组 CHD 的患病率与沙特阿拉伯其他地区和全球的报告一致。在本研究中，参与者的性别与 DS 患者 CHD 的发生无关。