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尼日利亚孤立性派杰氏错构瘤型错构瘤 1 例:罕见发现病例报告并文献复习

Solitary peutz-jeghers type hamartoma in a Nigerian: A case report of a rare finding and review of literature.

机构信息

ReMay Consultancy and Medical Services, Ikeja, Lagos State, Nigeria.

Department of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria.

出版信息

Ann Afr Med. 2021 Oct-Dec;20(4):307-309. doi: 10.4103/aam.aam_37_20.

Abstract

BACKGROUND

We report a case of solitary Peutz-Jeghers (P-J) type hamartomatous polyp in the sigmoid colon of an asymptomatic Nigerian without other diagnostic criteria for full-blown P-J syndrome.

CASE REPORT

During colonoscopy for a 58-year-old man, a solitary, pedunculated polyp was seen in the sigmoid colon. Histopathological examination of the endoscopically resected mass revealed the classical features of P-J type hamartoma. A search for lentigines on the skin or mucous buccal membranes was negative. There is no family history of such findings.

CONCLUSION

The case here presented is truly rare as a review of the scientific literature appears, to the best of our knowledge, not to contain such a unique presentation from our locality nor indeed from among Black Africans. We conducted a review of the literature and wished to highlight the evolving concept that solitary P-J polyps be considered a distinct disease entity when it appears in the absence of other features of the syndrome complex.

摘要

背景

我们报告了一例尼日利亚无症状患者的乙状结肠单发 Peutz-Jeghers(P-J)型错构瘤,该患者无 P-J 综合征的其他诊断标准。

病例报告

对一名 58 岁男性进行结肠镜检查时,在乙状结肠中发现了一个单发的有蒂息肉。内镜切除肿块的组织病理学检查显示出 P-J 型错构瘤的典型特征。皮肤或口腔颊黏膜上的黑斑检查结果为阴性。家族中没有此类发现的病史。

结论

据我们所知,目前所报告的病例非常罕见,因为我们查阅科学文献后,似乎并未在我们当地或非洲黑人中发现这种独特的表现。我们对文献进行了回顾,并希望强调一个不断发展的概念,即当单发 P-J 息肉在缺乏综合征复杂的其他特征时,应被视为一种独特的疾病实体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d196/8693740/580f4d2f642c/AAM-20-307-g001.jpg

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