ReMay Consultancy and Medical Services, Ikeja, Lagos State, Nigeria.
Department of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria.
Ann Afr Med. 2021 Oct-Dec;20(4):307-309. doi: 10.4103/aam.aam_37_20.
We report a case of solitary Peutz-Jeghers (P-J) type hamartomatous polyp in the sigmoid colon of an asymptomatic Nigerian without other diagnostic criteria for full-blown P-J syndrome.
During colonoscopy for a 58-year-old man, a solitary, pedunculated polyp was seen in the sigmoid colon. Histopathological examination of the endoscopically resected mass revealed the classical features of P-J type hamartoma. A search for lentigines on the skin or mucous buccal membranes was negative. There is no family history of such findings.
The case here presented is truly rare as a review of the scientific literature appears, to the best of our knowledge, not to contain such a unique presentation from our locality nor indeed from among Black Africans. We conducted a review of the literature and wished to highlight the evolving concept that solitary P-J polyps be considered a distinct disease entity when it appears in the absence of other features of the syndrome complex.
我们报告了一例尼日利亚无症状患者的乙状结肠单发 Peutz-Jeghers(P-J)型错构瘤,该患者无 P-J 综合征的其他诊断标准。
对一名 58 岁男性进行结肠镜检查时,在乙状结肠中发现了一个单发的有蒂息肉。内镜切除肿块的组织病理学检查显示出 P-J 型错构瘤的典型特征。皮肤或口腔颊黏膜上的黑斑检查结果为阴性。家族中没有此类发现的病史。
据我们所知,目前所报告的病例非常罕见,因为我们查阅科学文献后,似乎并未在我们当地或非洲黑人中发现这种独特的表现。我们对文献进行了回顾,并希望强调一个不断发展的概念,即当单发 P-J 息肉在缺乏综合征复杂的其他特征时,应被视为一种独特的疾病实体。