Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Rehabilitation Medicine, Asahi Neurology and Rehabilitation Hospital, Matsudo, Japan.
Geriatr Gerontol Int. 2022 Feb;22(2):127-131. doi: 10.1111/ggi.14328. Epub 2021 Dec 11.
Although frailty could be reversible by early diagnosis and interventions, it lacks definite diagnostic criteria. The Kihon Checklist is a 25-item questionnaire that diagnoses frailty with a cutoff score of 7/8. The Questionnaire for Medical Checkup of Old-Old (QMCOO) was recently established and used for medical checkups among Japanese older adults, but no method or cutoff score for diagnosing frailty has been established. Thus, we aimed to diagnose frailty using the QMCOO and to determine its cutoff score by comparing it with that of the Kihon Checklist.
We recruited 223 older adults in Yasugi City and Yonago City to answer all the questions in the Kihon Checklist and the QMCOO at the same time. Those scoring ≥8 for the Kihon Checklist (n = 38) were diagnosed as frail. We also determined the cutoff score for frailty for the QMCOO and examined which questionnaire items affected the frailty status.
The QMCOO and the Kihon Checklist score showed a significant positive correlation (r = 0.670, P < 0.001). The area under the curve was 0.851. A cutoff score of 3/4 for the QMCOO represented the best results (sensitivity, 76.3%; specificity, 88.1%; and accuracy, 86.1%). Multiple linear regression analysis revealed that subjective health status, body weight loss, slowness, and forgetfulness still affected the frailty status.
A cutoff score of 3/4 for the QMCOO might be effective in diagnosing frailty. Geriatr Gerontol Int 2022; 22: 127-131.
虽然虚弱可以通过早期诊断和干预来逆转，但它缺乏明确的诊断标准。《健康检查核对表》是一种包含 25 个项目的问卷，其诊断虚弱的临界值为 7/8 分。《老年医学健康检查问卷》（QMCOO）最近已建立并用于日本老年人的健康检查，但尚未确定诊断虚弱的方法或临界值。因此，我们旨在使用 QMCOO 诊断虚弱，并通过与《健康检查核对表》进行比较来确定其临界值。
我们在安昙市和米子市招募了 223 名老年人，要求他们同时回答《健康检查核对表》和 QMCOO 中的所有问题。《健康检查核对表》得分≥8 分的（n=38）被诊断为虚弱。我们还确定了 QMCOO 诊断虚弱的临界值，并检查了哪些问卷项目影响了虚弱状况。
QMCOO 和《健康检查核对表》得分呈显著正相关（r=0.670，P<0.001）。曲线下面积为 0.851。QMCOO 的 3/4 分作为临界值代表了最佳结果（灵敏度为 76.3%，特异性为 88.1%，准确性为 86.1%）。多元线性回归分析显示，主观健康状况、体重减轻、动作缓慢和健忘仍会影响虚弱状况。
QMCOO 的 3/4 分作为临界值可能有助于诊断虚弱。国际老年医学与老年学杂志 2022；22：127-131。
