Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
Department of Methodology and Statistics, Maastricht University Medical Center, Maastricht, The Netherlands.
J Neurol. 2022 Oct;269(10):5239-5248. doi: 10.1007/s00415-021-10909-8. Epub 2021 Dec 11.
Combining a mobile application-based vestibular diary called the DizzyQuest and an iPad-based hearing test enables evaluation of the relationship between experienced neuro-otological symptoms and hearing thresholds in daily life setting. The aim was to investigate the relationship between self-reported hearing symptoms and hearing thresholds in patients with Meniere's disease (MD), using the DizzyQuest and the iPad-based hearing test simultaneously.
The DizzyQuest was administered for 3 weeks in 21 patients. Using the experience-sampling-method (ESM), it assessed hearing loss and tinnitus severity for both ears separately. Each day after the DizzyQuest, an iPad-based hearing test was used to measure hearing thresholds. A mixed model regression analysis was performed to investigate relationships between hearing thresholds and self-reported hearing loss and tinnitus severity.
Fifteen patients were included. Overall, pure-tone averages (PTAs) were not correlated with self-reported hearing loss severity and tinnitus. Individual differences in PTA results between both ears did not significantly influence the difference in self-reported hearing loss severity between both ears. Self-reported hearing loss and tinnitus scores were significantly higher in ears that corresponded with audiometric criteria of MD (p < 0.001). Self-reported tinnitus severity significantly increased with self-reported hearing loss severity in affected (p = 0.011) and unaffected ears (p < 0.001).
Combining the DizzyQuest and iPad-based hearing test, facilitated assessment of self-reported hearing loss and tinnitus severity and their relationship with hearing thresholds, in a daily life setting. This study illustrated the importance of investigating neuro-otological symptoms at an individual level, using multiple measurements. ESM strategies like the DizzyQuest should therefore be considered in neuro-otological research.
结合基于移动应用的眩晕日记（称为 DizzyQuest）和基于 iPad 的听力测试，可以评估在日常生活环境中经历的神经耳科症状与听力阈值之间的关系。目的是使用 DizzyQuest 和基于 iPad 的听力测试同时研究梅尼埃病（MD）患者的自我报告听力症状与听力阈值之间的关系。
21 名患者在 3 周内完成了 DizzyQuest 的测试。使用体验采样法（ESM），分别评估了双耳的听力损失和耳鸣严重程度。在 DizzyQuest 测试后的每一天，都使用基于 iPad 的听力测试来测量听力阈值。进行混合模型回归分析以研究听力阈值与自我报告的听力损失和耳鸣严重程度之间的关系。
共纳入 15 名患者。总体而言，纯音平均值（PTA）与自我报告的听力损失严重程度和耳鸣无相关性。双耳 PTA 结果的个体差异并未显著影响双耳自我报告的听力损失严重程度之间的差异。与 MD 的听力学标准相符的耳朵的自我报告听力损失和耳鸣评分显著更高（p<0.001）。受影响（p=0.011）和未受影响的耳朵（p<0.001）的自我报告耳鸣严重程度均随自我报告听力损失严重程度的增加而显著增加。
结合 DizzyQuest 和基于 iPad 的听力测试，在日常生活环境中可以方便地评估自我报告的听力损失和耳鸣严重程度及其与听力阈值的关系。本研究说明了使用多种测量方法在个体水平上调查神经耳科症状的重要性。因此，ESM 策略（如 DizzyQuest）应在神经耳科学研究中得到考虑。
