亚胺培南对流感嗜血杆菌和副流感嗜血杆菌的体外活性比较
Comparative in vitro activity of imipenem against Haemophilus influenzae and Haemophilus parainfluenzae.
作者信息
Cerami A T, Shungu D L
出版信息
Antimicrob Agents Chemother. 1986 Jul;30(1):179-80. doi: 10.1128/AAC.30.1.179.
Abstract
A microdilution broth method was used to test 77 clinical isolates of Haemophilus influenzae and Haemophilus parainfluenzae, including beta-lactamase-positive and -negative strains, for susceptibility to ampicillin, chloramphenicol, and imipenem. Except for ampicillin against beta-lactamase-producing strains (MIC for 90% of strains [MIC90], greater than or equal to 128 micrograms/ml), all three antimicrobial agents had comparable in vitro activity (MIC90, less than or equal to 1 microgram/ml) against these bacterial strains.
摘要
采用微量稀释肉汤法检测了77株流感嗜血杆菌和副流感嗜血杆菌临床分离株，包括β-内酰胺酶阳性和阴性菌株，以测定它们对氨苄西林、氯霉素和亚胺培南的敏感性。除氨苄西林对产β-内酰胺酶菌株（90%菌株的最低抑菌浓度[MIC90]，大于或等于128微克/毫升）外，这三种抗菌药物对这些细菌菌株具有相当的体外活性（MIC90，小于或等于1微克/毫升）。
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本文引用的文献
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