Primary Health Care Corporation (PHCC), Doha, Qatar.
Research Unit, Physical Activity, Sport, and Health, UR18JS01, National Observatory of Sport, Tunis 1003, Tunisia.
Libyan J Med. 2022 Dec;17(1):2010337. doi: 10.1080/19932820.2021.2010337.
Many COVID-19 infected people remain asymptomatic, and hence the diagnosis at first presentation remains a challenge. Assessment at a presentation in primary care settings is usually done by visual triaging and basic clinical examination. This retrospective study involved investigating the medical e-records of COVID-19 positive patients who presented to a COVID-19 centre in Qatar for July 2020. The presence (symptomatic group) or the absence (asymptomatic group) of symptoms along with objective vital examination (; heart-rate (HR), temperature, haemoglobin saturation (SpO)) were analysed and linked to the viral load (; cycle threshold (Ct)) of COVID-19 positive patients. Four hundred eighty-one symptomatic (230 males) and 216 asymptomatic (101 males) patients were included. Compared to the asymptomatic male group, the symptomatic male group was older, had lower Ct value and SpO, and higher temperature and HR. Compared to the females asymptomatic group, the symptomatic females group had lower Ct value, and higher temperature. Compared to the asymptomatic group, the symptomatic group had lower Ct value and SpO, and higher temperature and HR. Compared to the asymptomatic group, the symptomatic group had lower Ct values (age groups [21-30], [31-40], [41-50] and [51-60]), higher temperature (age groups [21-30] and [31-40], Ct ranges [20.01-25.00] and [25.01-30.00]), higher HR (age groups [21-30] and [31-40], Ct range [15.01-20.00]); and lower SpO (age groups [41-50] and [51-60], Ct ranges [15.01-20.00] and [35.01-40.00]). Compared with asymptomatic patients, symptomatic patients with COVID-19 are most likely to be febrile, tachycardic, hypoxic and having higher viral load. Higher viral load was associated with higher HR, higher temperature, lower SpO, but there was no relation between viral load and age.
许多 COVID-19 感染者无症状，因此最初的诊断仍然是一个挑战。在基层医疗机构就诊时，评估通常通过视觉分诊和基本临床检查进行。本回顾性研究调查了 2020 年 7 月在卡塔尔的一个 COVID-19 中心就诊的 COVID-19 阳性患者的电子病历。分析了有无症状（症状组）以及客观生命体征（心率 (HR)、体温、血红蛋白饱和度 (SpO2))，并将其与 COVID-19 阳性患者的病毒载量（循环阈值 (Ct))相关联。共纳入 481 例有症状（230 例男性）和 216 例无症状（101 例男性）患者。与无症状男性组相比，症状男性组年龄较大，Ct 值和 SpO2 较低，体温和 HR 较高。与无症状女性组相比，有症状女性组的 Ct 值较低，体温较高。与无症状组相比，症状组的 Ct 值和 SpO2 较低，体温和 HR 较高。与无症状组相比，症状组的 Ct 值较低（年龄组 [21-30]、[31-40]、[41-50] 和 [51-60]），体温较高（年龄组 [21-30] 和 [31-40]，Ct 范围 [20.01-25.00] 和 [25.01-30.00]），HR 较高（年龄组 [21-30] 和 [31-40]，Ct 范围 [15.01-20.00]）；SpO2 较低（年龄组 [41-50] 和 [51-60]，Ct 范围 [15.01-20.00] 和 [35.01-40.00]）。与无症状患者相比，COVID-19 有症状患者更有可能发热、心动过速、缺氧，病毒载量更高。较高的病毒载量与较高的 HR、较高的体温、较低的 SpO2 相关，但病毒载量与年龄之间没有关系。
