• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

尿道成形术后无阿片类药物的镇痛途径。

A narcotic free pathway for postoperative pain following urethroplasty.

机构信息

Department of Urology, University of California, San Diego, California, USA.

Department of Urology, Virginia Mason, Seattle, Washington, USA.

出版信息

Can J Urol. 2021 Dec;28(6):10914-10919.

PMID:34895396
Abstract

INTRODUCTION

In an effort to decrease physician contribution to the opioid crisis, we utilized a narcotic free pathway (NFP) after urethroplasty. Our objectives were to demonstrate feasibility of a NFP and identify patients at higher risk for requiring postoperative narcotics.

MATERIALS AND METHODS

We implemented a NFP for patients undergoing urethroplasty. Pain was assessed using the Likert scale (1-10). Narcotic use was quantified using oral morphine equivalents (OMEs).

RESULTS

Forty-six patients underwent urethroplasty following the NFP over a 7-month period. Fifteen patients were excluded, leaving 31 patients in the final analysis. Postintervention data was compared to 30 patients who underwent urethroplasty prior to implementation of the NFP. The groups had similar demographics except for a history of heroin abuse (0% preintervention, 12.9% postintervention, p = 0.04). Surgical characteristics were not statistically different aside from length of surgery (183.6 minutes preintervention, 145.5 minutes postintervention, p = 0.01). The mean [SD] perioperative OME use preintervention was 194.9 [151] mg, compared to 40.4 [111.9] mg postintervention (p < 0.001). Six patients postintervention were discharged with a narcotic prescription (mean 27.5 mg OME) compared to 26 patients preintervention (mean 76 mg OME) (p < 0.001). There was no difference in pain scores at any time interval. Patients with a history of chronic opioid use were more likely to require narcotics (OR 5.33, CI 1-28.44).

CONCLUSIONS

The narcotic free pathway resulted in a dramatic reduction in narcotic prescriptions without a significant difference in postoperative pain scores. Opioid use can be minimized following urethral and perineal surgery.

摘要

简介

为了减少医生在阿片类药物危机中的贡献,我们在尿道成形术后采用了无麻醉剂途径(NFP)。我们的目标是证明 NFP 的可行性,并确定需要术后麻醉剂的患者的更高风险。

材料和方法

我们为接受尿道成形术的患者实施了 NFP。使用 Likert 量表(1-10)评估疼痛。使用口服吗啡当量(OME)量化麻醉剂的使用。

结果

在 7 个月的时间里,有 46 名患者接受了 NFP 下的尿道成形术。排除了 15 名患者,最终分析中剩下 31 名患者。干预后数据与 30 名在实施 NFP 之前接受尿道成形术的患者进行了比较。两组的人口统计学特征相似,但海洛因滥用史不同(干预前为 0%,干预后为 12.9%,p=0.04)。手术特点除手术时间外无统计学差异(干预前为 183.6 分钟,干预后为 145.5 分钟,p=0.01)。干预前围手术期 OME 使用的平均值[标准差]为 194.9[151]mg,干预后为 40.4[111.9]mg(p<0.001)。干预后有 6 名患者出院时开了麻醉处方(平均 27.5mg OME),而干预前有 26 名患者(平均 76mg OME)(p<0.001)。在任何时间间隔都没有疼痛评分的差异。有慢性阿片类药物使用史的患者更有可能需要麻醉剂(OR 5.33,CI 1-28.44)。

结论

无麻醉剂途径导致麻醉处方显著减少,而术后疼痛评分无显著差异。尿道和会阴手术后可以尽量减少阿片类药物的使用。

相似文献

1
A narcotic free pathway for postoperative pain following urethroplasty.尿道成形术后无阿片类药物的镇痛途径。
Can J Urol. 2021 Dec;28(6):10914-10919.
2
Impact of Enhanced Recovery After Surgery and Opioid-Free Anesthesia on Opioid Prescriptions at Discharge From the Hospital: A Historical-Prospective Study.术后加速康复和非阿片类麻醉对出院时阿片类药物处方的影响:一项历史前瞻性研究。
Anesth Analg. 2017 Nov;125(5):1784-1792. doi: 10.1213/ANE.0000000000002510.
3
A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study.一种用于骨盆重建手术患者的疼痛管理综合模型:一项前瞻性临床实践研究。
Am J Obstet Gynecol. 2020 Aug;223(2):262.e1-262.e8. doi: 10.1016/j.ajog.2020.05.019. Epub 2020 May 13.
4
Patient-Centered Decision-making for Postoperative Narcotic-Free Endocrine Surgery: A Randomized Clinical Trial.以患者为中心的决策在术后无阿片类药物内分泌手术中的应用:一项随机临床试验。
JAMA Surg. 2021 Nov 1;156(11):e214287. doi: 10.1001/jamasurg.2021.4287. Epub 2021 Nov 10.
5
Early In-Hospital Pain Control Is a Stronger Predictor for Patients Requiring a Refill of Narcotic Pain Medication Compared to the Amount of Narcotics Given at Discharge.与出院时给予的麻醉性镇痛药剂量相比,早期住院疼痛控制是患者需要再次开麻醉性镇痛药的更强预测因素。
J Arthroplasty. 2019 Jul;34(7):1354-1358. doi: 10.1016/j.arth.2019.02.059. Epub 2019 Mar 6.
6
A Multi-institutional Assessment of Multimodal Analgesia in Penile Implant Recipients Demonstrates Dramatic Reduction in Pain Scores and Narcotic Usage.多模式镇痛在阴茎植入患者中的多机构评估显示疼痛评分和麻醉药物使用量显著降低。
J Sex Med. 2020 Mar;17(3):518-525. doi: 10.1016/j.jsxm.2019.11.267. Epub 2019 Dec 20.
7
Characterizing the Effect of Perioperative Narcotic Consumption and Narcotic Prescription Dosing at Discharge on Satisfaction With Pain Control for Patients Undergoing Single-level Anterior Cervical Discectomy and Fusion.描述围手术期阿片类药物消耗和出院时阿片类药物处方剂量对行单节段前路颈椎间盘切除融合术患者疼痛控制满意度的影响。
Clin Spine Surg. 2022 Jun 1;35(5):E478-E482. doi: 10.1097/BSD.0000000000001279. Epub 2021 Dec 15.
8
Association of Perioperative Opioid-Sparing Multimodal Analgesia With Narcotic Use and Pain Control After Head and Neck Free Flap Reconstruction.围手术期阿片类药物节俭型多模式镇痛与头颈部游离皮瓣重建术后阿片类药物使用和疼痛控制的关系。
JAMA Facial Plast Surg. 2019 Sep 1;21(5):446-451. doi: 10.1001/jamafacial.2019.0612.
9
Perioperative Opioid and Nonopioid Prescribing Patterns in AVF/AVG Creation.动静脉内瘘/移植物创建术围手术期阿片类药物和非阿片类药物的开具模式。
Ann Vasc Surg. 2021 Apr;72:290-298. doi: 10.1016/j.avsg.2020.09.002. Epub 2020 Sep 16.
10
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.随机、双盲、安慰剂对照试验比较经蝶窦手术后两种多模式减少阿片类药物的疼痛管理方案。
J Neurosurg. 2018 Feb;128(2):444-451. doi: 10.3171/2016.10.JNS161355. Epub 2017 Mar 3.

引用本文的文献

1
Narcotic Requirements before and after Implementation of Buccal Nerve Blocks for Buccal Mucosa Graft Harvest: Technique and Retrospective Review.用于颊黏膜移植的颊神经阻滞实施前后的麻醉剂需求:技术与回顾性研究
J Clin Med. 2023 Mar 10;12(6):2168. doi: 10.3390/jcm12062168.