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Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy.

作者信息

Li Shujin, Yang Mu, He Yunqi, Jiang Xiaoyan, Zhao Rulian, Liu Wenjing, Huang Lulin, Shi Yi, Li Xiao, Sun Kuanxiang, Yang Yeming, Sundaresan Periasamy, Zhao Peiquan, Yang Zhenglin, Zhu Xianjun

机构信息

Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China; Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China; Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China.

Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China.

出版信息

J Genet Genomics. 2022 Jun;49(6):590-594. doi: 10.1016/j.jgg.2021.11.010. Epub 2021 Dec 9.

DOI:10.1016/j.jgg.2021.11.010
PMID:34896607
Abstract
摘要

相似文献

1
Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy.Wnt 共受体低密度脂蛋白受体相关蛋白 6（LRP6）的变异与家族性渗出性玻璃体视网膜病变有关。
J Genet Genomics. 2022 Jun;49(6):590-594. doi: 10.1016/j.jgg.2021.11.010. Epub 2021 Dec 9.
2
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3
Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy.整合素连接激酶控制视网膜血管生成，与 Wnt 信号通路和渗出性玻璃体视网膜病变有关。
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Downregulated low-density lipoprotein receptor-related protein 6 induces the maldevelopment of extravillous trophoblast via Wnt/β-catenin signaling pathway.下调低密度脂蛋白受体相关蛋白 6 通过 Wnt/β-连环蛋白信号通路诱导绒毛外滋养细胞发育不良。
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Osteoarthritis Cartilage. 2013 Oct;21(10):1576-85. doi: 10.1016/j.joca.2013.05.019. Epub 2013 Jun 10.

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Invest Ophthalmol Vis Sci. 2025 Feb 3;66(2):23. doi: 10.1167/iovs.66.2.23.
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Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy.Calcyphosine-like 基因功能障碍通过 MYC 轴损害视网膜血管生成，并与家族性渗出性玻璃体视网膜病变有关。
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