红细胞分布宽度作为急性前循环缺血性脑卒中血管内治疗 1 年预后和死亡率的预测指标。
Red Cell Distribution Width as a Predictor of One-Year Prognosis and Mortality of Endovascular Therapy for Acute Anterior Circulation Ischemic Stroke.
机构信息
Jiangsu Taizhou People's Hospital, Taizhou 225300, China.
Jiangsu Taizhou People's Hospital, Taizhou 225300, China.
出版信息
J Stroke Cerebrovasc Dis. 2022 Feb;31(2):106243. doi: 10.1016/j.jstrokecerebrovasdis.2021.106243. Epub 2021 Dec 10.
OBJECTIVES
To investigate if Red cell distribution width (RDW) can predict long-term prognosis in patients with acute ischemic stroke (AIS) receiving endovascular therapy (EVT).
METHODS
In this study, 102 AIS patients treated with EVT were retrospectively recruited. Clinical profiles and prognoses were collected for all patients. The patients were grouped following the modified ranking scale (MRS) scoring system as given below: a group of favorable functional outcome: 0-2; and a group of unfavorable functional outcome: 3-6.
RESULTS
In multivariate logistic regression, RDW (odds ratio [OR] = 2.799, 95 % confidence interval [CI] = 1.425-5.489; p = 0.003) was an independent predictor of unfavorable functional outcome, and it (OR, 1.929; 95% CI, 1.075-3.458; p = 0.028) was also an independent biomarker for all-cause mortality. The best predictive RDW cut-off value was 13.05% (sensitivity: 93.1%, specificity: 60.3%, AUC: 0.806, p < 0.001).
CONCLUSIONS
The results imply that pre-RDW is a reliable predictor of one-year prognosis and mortality after EVT in acute anterior circulation stroke patients.
目的
探讨红细胞分布宽度（RDW）能否预测接受血管内治疗（EVT）的急性缺血性脑卒中（AIS）患者的长期预后。
方法
本研究回顾性纳入 102 例接受 EVT 治疗的 AIS 患者。收集所有患者的临床特征和预后。根据改良Rankin 量表（MRS）评分系统将患者分为以下两组：功能结局良好组（MRS 评分 0-2 分）和功能结局不良组（MRS 评分 3-6 分）。
结果
多因素 logistic 回归分析显示，RDW（比值比 [OR] = 2.799，95%置信区间 [CI] = 1.425-5.489；p = 0.003）是功能结局不良的独立预测因子，其（OR，1.929；95%CI，1.075-3.458；p = 0.028）也是全因死亡率的独立生物标志物。预测 RDW 的最佳截断值为 13.05%（灵敏度：93.1%，特异性：60.3%，AUC：0.806，p < 0.001）。
结论
这些结果表明，RDW 可作为急性前循环卒中患者 EVT 后 1 年预后和死亡率的可靠预测指标。
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