Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA.
Department of Oral and Maxillofacial Surgery, Detroit Receiving Hospital, Detroit, MI.
J Craniofac Surg. 2022 Jun 1;33(4):1082-1089. doi: 10.1097/SCS.0000000000008432. Epub 2021 Dec 10.
Prophylactic antibiotics are commonly used in the management of traumatic injuries to the maxillofacial complex, yet there are no set guidelines for when and when not to prescribe. The purpose of this review is to present the evidence for antibiotic prophylaxis in different clinical scenarios and to propose algorithms to facilitate the decision making process with the ultimate goal of improving antibiotic prescribing practices. A number of databases were searched using a wide range of keywords to ensure the topic was fully encapsulated. The review is divided into 3 sections: soft tissue trauma, maxillofacial fractures, and ballistic injuries. The algorithms were constructed using the current evidence as well as pathophysiologic principles, especially when there were insufficient studies. This review found the literature on antibiotic prophylaxis to be highly varied and not standardized. Creating an algorithm for providers to follow will help to set a standard of care and decrease the misuse of antibiotics.
预防性抗生素在治疗颌面外伤中被广泛应用,但何时应用及何时不应应用却没有明确的指导原则。本文的目的是为不同临床情况下的抗生素预防提供循证医学证据,并提出便于决策的算法,最终目标是改善抗生素的应用。我们使用了多种关键词在多个数据库中进行了检索,以确保全面涵盖了这一主题。本文综述分为软组织创伤、颌面骨折和弹道伤 3 个部分。算法的构建不仅基于现有的证据,还基于病理生理学原理,特别是在研究不足的情况下。本研究发现,抗生素预防的文献高度多样化,且未标准化。为提供者创建一个遵循的算法将有助于设定护理标准,并减少抗生素的滥用。