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恒河猴（Macaca mulatta）幼年白内障继发青光眼的临床特征、治疗及遗传和组织病理学分析。

Clinical presentation, treatment, and genetic and histopathological analysis of juvenile cataracts and secondary glaucoma in a rhesus macaque (Macaca mulatta).

机构信息

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.

出版信息

J Med Primatol. 2022 Apr;51(2):119-123. doi: 10.1111/jmp.12560. Epub 2021 Dec 12.

DOI:10.1111/jmp.12560
PMID:34897697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8897224/
Abstract

This report describes the clinical and histological findings, genetic study, and treatment in a 1.3-year-old rhesus macaque with bilateral cataracts and unilateral secondary glaucoma. Intravitreal injection of gentamicin decreased the intraocular pressure from 56 to <2 mm Hg. A putative genetic cause of the cataracts was not identified.

摘要

本报告描述了一只 1.3 岁恒河猴的临床和组织学发现、基因研究和治疗情况，该猴患有双侧白内障和单侧继发黄斑性青光眼。玻璃体内注射庆大霉素使眼内压从 56 降至 <2mmHg。未发现白内障的潜在遗传原因。

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J Med Primatol. 2022 Apr;51(2):119-123. doi: 10.1111/jmp.12560. Epub 2021 Dec 12.
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本文引用的文献

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Inherited cataracts: molecular genetics, clinical features, disease mechanisms and novel therapeutic approaches.遗传性白内障：分子遗传学、临床特征、发病机制和新的治疗方法。
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Measurement of plasma gentamicin concentrations postchemical ciliary body ablation in dogs with chronic glaucoma.慢性青光眼犬化学性睫状体消融术后血浆庆大霉素浓度的测定
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