Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
J Surg Oncol. 2022 Jan;125(1):38-45. doi: 10.1002/jso.26746.
Adjuvant systemic therapy for cutaneous melanoma has experienced practice-changing shifts over the last decade. The successful results of immunotherapies and targeted therapies in the metastatic setting have allowed for investigative trials of the same therapies in the adjuvant and now neoadjuvant setting, with the potential for improved clinical outcomes in patients with high risk resected Stage III and IV melanoma.
在过去十年中，皮肤黑色素瘤的辅助全身治疗经历了重大变革。免疫疗法和靶向治疗在转移性疾病中的成功结果，使得在辅助治疗和现在的新辅助治疗中探索这些治疗方法成为可能，这有可能改善高风险 III 期和 IV 期黑色素瘤切除患者的临床结局。
