Liang Da-Ting, Dai Xu-Chao, Sun Fa
Graduate School, Guizhou Medical University, Guiyang, Guizhou 550004, China.
Department of Urology, People's Hospital of Guizhou Province, Guiyang, Guizhou 550004, China.
Zhonghua Nan Ke Xue. 2020 Nov;26(11):1030-1034.
Bisphenol A (BPA), a common endocrine disrupting chemical, is becoming a focus of studies and receiving increasing attention. Because of its wide use in food packaging materials, receipt paper, dental sealant and other products, people contact it through the skin, respiratory tract, digestive system and other routes. A large number of studies at home and abroad have shown that BPA exposure can adversely affect male reproductive function, including semen quality, spermatogenesis, sperm epigenetic inheritance, etc. Its action mechanisms, however, remain unclear and require more studies. This review focuses on the impacts of BPA exposure on spermatogenesis in males.
双酚A（BPA）是一种常见的内分泌干扰化学物质，正成为研究的焦点并受到越来越多的关注。由于其在食品包装材料、收据纸、牙科密封剂和其他产品中的广泛使用，人们通过皮肤、呼吸道、消化系统等途径接触到它。国内外大量研究表明，接触双酚A会对男性生殖功能产生不利影响，包括精液质量、精子发生、精子表观遗传遗传等。然而，其作用机制仍不清楚，需要更多的研究。这篇综述重点关注双酚A暴露对男性精子发生的影响。
