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针对 COVID-19 的异源初免-加强接种:安全且可靠吗?

Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?

机构信息

Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, India.

Independent Researcher, 07, Type IV Quarter, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, India.

出版信息

Hum Vaccin Immunother. 2021 Dec 2;17(12):5135-5138. doi: 10.1080/21645515.2021.2007015. Epub 2021 Dec 13.

DOI:10.1080/21645515.2021.2007015
PMID:34898381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8726007/
Abstract

Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the rapidly emerging SARS-CoV-2 variants. Many studies have been conducted on the heterologous prime-boost vaccine regimens and have shown good efficacy results against COVID-19. This article aims to highlight the safety and reliability of heterologous prime-boost vaccination against COVID-19. We have also made some recommendations towards using these combinations of vaccines for the global mitigation of the subsequent waves of COVID-19.

摘要

在全球范围内,许多国家正在努力应对 COVID-19 的连续波。已经使用了几种疫苗来克服这一持续的大流行,并可作为单剂和双剂接种;然而,由于 SARS-CoV-2 变体的迅速出现,同源疫苗的效力正在重新考虑。已经对异源初免-加强疫苗方案进行了许多研究,并显示出对 COVID-19 的良好疗效结果。本文旨在强调针对 COVID-19 的异源初免-加强疫苗接种的安全性和可靠性。我们还就使用这些疫苗组合为全球减轻 COVID-19 的后续浪潮提出了一些建议。

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Hum Vaccin Immunother. 2021 Nov 2;17(11):4117-4118. doi: 10.1080/21645515.2021.1960770. Epub 2021 Aug 6.
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Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2.采用ChAdOx1 nCoV-19和BNT162b2进行异源初免-加强免疫接种。
Lancet Infect Dis. 2021 Sep;21(9):1212-1213. doi: 10.1016/S1473-3099(21)00420-5. Epub 2021 Jul 29.
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N Engl J Med. 2021 Sep 9;385(11):1049-1051. doi: 10.1056/NEJMc2110716. Epub 2021 Jul 14.
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