Elbardisy Hadeel, Abedalthagafi Malak
Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Front Genet. 2021 Nov 25;12:759662. doi: 10.3389/fgene.2021.759662. eCollection 2021.
"Women in much of the world lack support for fundamental functions of a human life." This truthful portrait was pointed out by Martha Nussbaum in her book " Throughout history, gender inequality has been persistent in many aspects of life, including health and empowerment. Unfortunately, this inequality has not been excluded from the field of science. Perpetual assumption that women's absence or restriction to secondary roles in various disciplines is an acceptable law of nature misrepresents women's contribution to science and maintains hurdles for participation in the future. According to a recent UNESCO's report, women make up only 30% of researchers worldwide. But despite all the obstacles, women made major contributions with discoveries that shaped the progress in many scientific fields. In the field of genetics, Rosalind Franklin is an example of unwittingly compromised women's scientific achievements. Franklin was an expert in X-ray crystallography; her data, especially the "photo 51," was critical to James Watson and Francis Crick along with their own data to publish the discovery of the double helix DNA structure in 1953. Her contribution was acknowledged posthumously in Watson's memoir in 1968. Barbara McClintock was a 20th century American cytogeneticist who remains up to date the only woman receiving an unshared Nobel prize in Physiology or Medicine. McClintock dedicated her work to cytogenetics and discovered the phenomenon of mobile genes. Her research was initially subjected to skepticism in the 1950s. It was not until the late 1960s that the community realized the significance of McClintock's discovery. The history of science is occupied with a myriad of similar tales of such inspiring women that, after tremendous struggles, thrived and achieved breakthroughs in their respective fields. It is prominent our limited knowledge of women's experience and struggle in science in non-western world. Addressing the stories of this outstanding minority is critical to expand the understanding of the gender disparity factors embedded in diverse cultures. In this article, we attempt to put the spotlight on some fascinating non-western women and their significant contributions to the field of genetics.
“世界上许多地方的女性在人类生活的基本功能方面缺乏支持。”玛莎·努斯鲍姆在她的书中指出了这一真实写照。纵观历史,性别不平等在生活的许多方面一直存在,包括健康和赋权。不幸的是,这种不平等在科学领域也未能幸免。长期以来,人们一直认为女性在各个学科中缺席或扮演次要角色是一种可接受的自然法则,这歪曲了女性对科学的贡献,并为她们未来的参与设置了障碍。根据联合国教科文组织最近的一份报告,全球研究人员中女性仅占30%。但尽管存在种种障碍,女性还是做出了重大贡献,她们的发现推动了许多科学领域的进步。在遗传学领域,罗莎琳德·富兰克林就是一个女性科学成就被无意损害的例子。富兰克林是X射线晶体学专家;她的数据,尤其是“照片51”,对詹姆斯·沃森和弗朗西斯·克里克至关重要,他们利用自己的数据以及富兰克林的数据,于1953年发表了双螺旋DNA结构的发现。她的贡献在1968年沃森的回忆录中才被追授认可。芭芭拉·麦克林托克是20世纪美国细胞遗传学家,至今仍是唯一一位独自获得诺贝尔生理学或医学奖的女性。麦克林托克致力于细胞遗传学研究,发现了移动基因现象。她的研究在20世纪50年代最初遭到怀疑。直到20世纪60年代末,科学界才意识到麦克林托克发现的重要性。科学史上充斥着无数类似的故事,讲述着这些鼓舞人心的女性在经历巨大斗争后,在各自领域蓬勃发展并取得突破。很明显,我们对非西方世界女性在科学领域的经历和斗争了解有限。讲述这些杰出少数群体的故事对于扩大对不同文化中性别差异因素的理解至关重要。在本文中,我们试图聚焦一些迷人的非西方女性及其对遗传学领域的重大贡献。