Singh Manavotam, Krishnan Mrinalini, Ghazzal Amre, Halushka Marc, Tozzi James E, Bunning Robert D, Rodrigo Maria E, Najjar Samer S, Molina Ezequiel J, Sheikh Farooq H
Advanced Heart Failure, MedStar Heart and Vascular Institute, Washington, DC, USA.
Department of Pathology, John Hopkins University, Baltimore, Maryland, USA.
CJC Open. 2021 Jun 26;3(11):1392-1395. doi: 10.1016/j.cjco.2021.06.010. eCollection 2021 Nov.
Infiltrative cardiomyopathies are an increasingly recognized cause of heart failure warranting systematic evaluation. Given overlap of clinical and imaging findings among etiologies of infiltrative cardiomyopathies, comprehensive evaluation, including a history and physical examination, advanced cardiac imaging, and sometimes endomyocardial biopsy, is required for diagnosis. We report a case of infiltrative cardiomyopathy in which endomyocardial biopsy confirmed diagnosis of cobalt-induced cardiomyopathy. The novel teaching points highlighted by this case report include identification of heavy-metal toxicity as a cause of infiltrative cardiomyopathy, and the outline of a diagnostic approach and management for cobalt-induced cardiomyopathy.
浸润性心肌病是导致心力衰竭的一个日益被认识到的原因,需要进行系统评估。鉴于浸润性心肌病病因之间临床和影像学表现存在重叠,诊断需要进行全面评估,包括病史和体格检查、先进的心脏成像,有时还需要进行心内膜心肌活检。我们报告一例浸润性心肌病病例,心内膜心肌活检确诊为钴诱导的心肌病。本病例报告突出的新教学要点包括识别重金属毒性作为浸润性心肌病的一个病因,以及概述钴诱导的心肌病的诊断方法和管理。