Department of Applied Chemistry, Kyushu University, Fukuoka 819-0395, Japan.
Centre for Polymer Interface and Molecular Adhesion Science, Kyushu University, Fukuoka 819-0395, Japan.
Langmuir. 2021 Dec 28;37(51):14911-14919. doi: 10.1021/acs.langmuir.1c02776. Epub 2021 Dec 13.
The mechanical properties in the outermost region of a polymer film strongly affect various material functions. We here propose a novel and promising strategy for the two-dimensional regulation of the mechanical properties of a polymer film at the water interface based on an inkjet drawing of silica nanoparticles (SNPs) underneath it. A film of poly(2-hydroxyethyl methacrylate) (PHEMA), which exhibits excellent bioinertness properties at the water interface, was well fabricated on a substrate with a pattern of SNPs. X-ray photoelectron spectroscopy and atomic force microscopy confirmed that the surface of the PHEMA film was flat and chemically homogeneous. However, the film surface was in-plane heterogeneous in stiffness due to the presence of the underlying SNP lines. It was also noted that NIH/3T3 fibroblast cells selectively adhered and formed aggregates on the areas under which an SNP line was drawn.
聚合物薄膜最外层的力学性能强烈影响着各种材料的功能。我们在此提出了一种新颖且有前景的策略，即在水下通过喷墨打印的方法将二氧化硅纳米粒子（SNPs）绘制在聚合物薄膜的最外层，以此来实现对聚合物薄膜二维力学性能的调控。在水下具有良好生物惰性的聚（2-羟乙基甲基丙烯酸酯）（PHEMA）薄膜可以在具有 SNPs 图案的基底上进行很好的制备。X 射线光电子能谱和原子力显微镜证实，PHEMA 薄膜的表面是平坦且化学均匀的。然而，由于底层 SNP 线的存在，薄膜表面在刚性方面呈现出面内各向异性。还注意到，NIH/3T3 成纤维细胞选择性地在 SNP 线绘制的区域附着并形成聚集体。
