Department of Psychiatry & Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA.
Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
Aust N Z J Psychiatry. 2022 Oct;56(10):1357-1362. doi: 10.1177/00048674211066004. Epub 2021 Dec 14.
Trichotillomania is characterized by repetitive pulling out of one's hair, leading to distress and/or functional impairment. Long considered a chronic condition if left untreated (albeit with fluctuating intensity), there have been intimations that the disorder may be of limited duration in some people.
A sample of 10,169 adults, aged 18-69 years, representative of the general US population, were recruited and screened for current and lifetime trichotillomania. Potential differences in demographic and clinical variables and lifetime comorbidities, between those with natural recovery from trichotillomania, and those with current trichotillomania, were identified using analysis of variance or likelihood-ratio chi-square tests as appropriate. Additional analyses using binary logistic regression were used to control for potential confounding differences between the groups initially identified.
In total, 24.9% of the entire sample of people with lifetime trichotillomania reported that they no longer had symptoms of trichotillomania and had never received therapy or medication treatment for it (i.e. they experienced natural recovery). Those who experienced natural recovery did not differ from those with current trichotillomania in terms of demographic or clinical characteristics, except that they were currently older. Natural recovery was associated with significantly lower rates of related comorbidities: obsessive-compulsive disorder, attention-deficit hyperactivity disorder, panic disorder, skin picking disorder and tic disorder.
These findings from the first epidemiology study examining natural recovery in trichotillomania highlight the importance of screening for and treating such comorbidities in patients with trichotillomania, in order to maximize chance of clinical recovery.
拔毛癖的特征是反复拉扯自己的头发,导致痛苦和/或功能障碍。如果不治疗(尽管强度波动),长期以来一直被认为是一种慢性疾病,但有迹象表明,这种疾病在某些人中可能是有限的持续时间。
招募了一个代表美国一般人群的 10169 名 18-69 岁成年人的样本,并对其进行了当前和终生拔毛癖的筛查。使用方差分析或似然比卡方检验,根据需要,对那些从拔毛癖中自然康复的人与那些目前患有拔毛癖的人在人口统计学和临床变量以及终生共病方面的潜在差异进行了识别。使用二元逻辑回归进行的额外分析用于控制最初确定的两组之间潜在的混杂差异。
在整个有终生拔毛癖史的人群中,有 24.9%的人报告说他们不再有拔毛癖的症状,并且从未接受过治疗或药物治疗(即他们自然康复了)。与目前患有拔毛癖的人相比,那些自然康复的人在人口统计学或临床特征方面没有差异,只是他们目前年龄更大。自然康复与相关共病的发生率显著降低有关:强迫症、注意缺陷多动障碍、惊恐障碍、皮肤搔抓障碍和抽动障碍。
这是第一项研究拔毛癖自然康复的流行病学研究结果,强调了在拔毛癖患者中筛查和治疗这些共病的重要性,以最大程度地提高临床康复的机会。