Hastings Cent Rep. 2021 Nov;51 Suppl 2:S74-S84. doi: 10.1002/hast.1323.
Proposals to release genetically engineered organisms in the wild raise complex ethical issues related to their safe and equitable implementation. While there is broad agreement that community and public engagement is vital to decision-making in this context, more discussion is needed about who should be engaged in such activities and in what ways. This article identifies Indigenous peoples as key stakeholders in decisions about gene-editing in the wild and argues that engagement activities need not only include Indigenous peoples but also be designed, conducted, and analyzed in ways that confront longstanding power imbalances that dismiss Indigenous expertise. We offer specific recommendations to guide deliberative activities to not only be inclusive of Indigenous peoples but also to empower their diverse, situated knowledges. We call on those committed to the inclusive design of broad public deliberation to pursue strategies that shift dominant power dynamics to include Indigenous communities in more meaningful ways.
将基因工程生物释放到野外的提议引发了与安全和公平实施相关的复杂伦理问题。尽管人们普遍认为,社区和公众的参与对于这方面的决策至关重要,但仍需要更多的讨论,包括应该让哪些人参与此类活动,以及以何种方式参与。本文认为,土著人民是决定野外基因编辑的关键利益攸关方,并认为参与活动不仅应包括土著人民,而且还应以克服长期以来忽视土著专业知识的权力失衡的方式来设计、进行和分析。我们提出了具体建议,以指导审议活动,不仅要包容土著人民,还要赋予他们多样化的、特定情境的知识权力。我们呼吁那些致力于广泛公众审议包容性设计的人,寻求改变主导权力动态的策略,以更有意义的方式将土著社区纳入其中。