Guselkumab 治疗银屑病患者并发矛盾性银屑病关节炎。
Paradoxical psoriatic arthritis in a patient with psoriasis treated with guselkumab.
机构信息
Rheumatology Institute of Lucania (IReL), Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.
Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy.
出版信息
Clin Exp Dermatol. 2022 Apr;47(4):783-785. doi: 10.1111/ced.15061. Epub 2022 Jan 5.
PMID:34905263
Abstract
Paradoxical psoriatic arthritis (PPsA) may be associated with guselkumab treatment. We describe a patient in whom PPsA required a change from guselkumab to ixekizumab. The pathophysiology of this paradoxical reaction is most likely a cytokine imbalance.
摘要
反常性银屑病关节炎（PPsA）可能与古塞丽珠单抗治疗有关。我们描述了一例 PPsA 患者需要从古塞丽珠单抗转换为依奇珠单抗治疗的病例。这种反常反应的病理生理学很可能是细胞因子失衡。
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