Figueras M J, Jongebloed W L, Worst J G
J Cataract Refract Surg. 1986 Sep;12(5):523-8. doi: 10.1016/s0886-3350(86)80127-4.
Extracapsular surgery was performed on a rabbit eye for implantation of a lobster-claw or iris-bridge type intraocular lens (IOL). The incision was closed with stainless steel-vanadium sutures of 50 micron diameter. Two months after implantation, one pincer of the lens became detached from the iris, causing an intermittent IOL-endothelial touch of four months duration. It resulted in endothelial disruption with localized breaks in Descemet's membrane. Six months after implantation, the IOL and the entire anterior segment were removed and processed for scanning electron microscopy. The lobster-claw lens had been covered partly with a membrane, composed of different types of cells with many microvilli, particularly in the vicinity of the loophole of the intact iris bridge. The sutures were almost completely covered with somewhat irregular endothelial cells and an intact Descemet's membrane. At isolated spots where the covering was incomplete, elongated cells with many microvilli bordered the open areas. At the site of breaks, Descemet's membrane was denuded and in the process of being repopulated with cells. At places of minor disruption, elongated and triangular-shaped endothelial cells, often having many microvilli and interconnections with philopodia-like extensions, were about to cover the "wounded" area.
对兔眼进行囊外手术以植入龙虾爪型或虹膜桥型人工晶状体(IOL)。切口用直径50微米的不锈钢钒缝线缝合。植入后两个月,晶状体的一个钳夹从虹膜分离,导致人工晶状体与内皮细胞间歇性接触持续四个月。这导致内皮细胞破坏,后弹力膜出现局部破裂。植入后六个月,取出人工晶状体和整个前段并进行扫描电子显微镜检查。龙虾爪型晶状体部分被一层膜覆盖,该膜由具有许多微绒毛的不同类型细胞组成,特别是在完整虹膜桥的漏洞附近。缝线几乎完全被有些不规则的内皮细胞和完整的后弹力膜覆盖。在覆盖不完全的孤立部位,具有许多微绒毛的细长细胞围绕着开放区域。在破裂部位,后弹力膜裸露,正处于细胞重新填充的过程中。在轻微破坏的部位,细长的三角形内皮细胞,通常具有许多微绒毛并通过丝状伪足样延伸相互连接,即将覆盖“受伤”区域。