Smith Alexander C, Nikkhah Dariush, Wade Ryckie
Plastic Surgery, Guy's and St Thomas' NHS Foundation Trust, London, GBR.
Plastic Surgery, Royal Free Hospital, London, GBR.
Cureus. 2021 Dec 5;13(12):e20183. doi: 10.7759/cureus.20183. eCollection 2021 Dec.
Background Digital replantation is associated with a substantial risk of failure. There is considerable variation in survival rates globally, and the current data are limited by poor statistical methods and bias of selection, which limits its translation to Europe and the USA. We aimed to establish a more representative survival rate of digit replantation for western populations and evaluate espoused prognostic variables using robust statistical methodology. Materials and Methods Retrospective data were collected from 58 consecutive patients who underwent digital replantation following traumatic amputation in three tertiary care hand centres in the UK over seven years. The unit of analysis was the digit. Generalized linear modelling was used to estimate the odds ratio (OR) of digit survival. Results Forty-six of 68 replanted digits survived (68%). The typical replant candidate was a 40-year-old male manual worker. Digit survival was more likely with guillotine injuries (adjusted OR 25.5 [95% CI 5.60, 115]) and when intraoperative skeletal shortening was performed (adjusted OR 15.3 [95% CI 2.62, 89.5]). The age of the patient, seniority of the operating surgeon, and use of vein grafts was not associated with digit survival. Conclusion We provide robust data to show that guillotine amputations have more favourable survival rates, which can be further improved by skeletal shortening at the time of replantation. We suggest that research networks worldwide set up digit amputation registries to capture individual patient data on this uncommon injury.
背景 手指再植失败风险很大。全球存活率存在显著差异,目前的数据受统计方法欠佳和选择偏倚的限制,这限制了其在欧洲和美国的应用。我们旨在为西方人群建立更具代表性的手指再植存活率,并使用可靠的统计方法评估公认的预后变量。材料与方法 回顾性收集了英国三个三级护理手部中心7年间58例创伤性截肢后接受手指再植的连续患者的数据。分析单位为手指。采用广义线性模型估计手指存活的比值比(OR)。结果 68根再植手指中有46根存活(68%)。典型的再植候选者是40岁的男性体力劳动者。切割伤(调整后OR 25.5 [95% CI 5.60, 115])以及进行术中骨骼缩短时(调整后OR 15.3 [95% CI 2.62, 89.5])手指存活的可能性更大。患者年龄、手术医生资历和使用静脉移植物与手指存活无关。结论 我们提供了可靠数据表明切割伤的存活率更高,再植时进行骨骼缩短可进一步提高存活率。我们建议全球研究网络建立手指截肢登记处,以收集关于这种罕见损伤的个体患者数据。