Alhassan Abdulrahman M, Alghunaim Mohammed N, Alqarni Ayyob A, Abdullah Abdulkareem M, Altoyan Mohammed K, Alharbi Abdullah S, Alhusain Faisal A
Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, SAU.
General Surgery, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, SAU.
Cureus. 2021 Dec 7;13(12):e20223. doi: 10.7759/cureus.20223. eCollection 2021 Dec.
Background Incisional hernia post organ transplant increases morbidity and impacts quality of life among patients undergoing abdominal organ transplants. Objectives To estimate the incidence rate of incisional hernia and the factors associated with incisional hernia among patients who underwent liver and kidney transplants. Methods This was a retrospective cohort study in which all patients from 2015 to 2020 who underwent liver and/or kidney transplants and met inclusion criteria were involved. Results A total of 424 patients who received transplantation surgery were included. Out of them, 287 patients (67.6%) underwent kidney transplants while 132 patients (31.1%) underwent a liver transplant. Additionally, five patients (1.1%) received both liver and kidney transplantation. Fourteen patients (3.3%) experienced incisional hernia across all samples. A higher incidence rate was noticed among patients with liver transplants compared to kidney transplants (6.81% in the liver group vs 1.7% in the kidney group), which showed a statistical significance between the two groups (P-value= 0.007). In multivariate analysis, surgical site infection (SSI), donor type, acute organ rejection, mycophenolate mofetil (MMF), and diabetes were all not predictors of incisional hernia among the patients. Conclusion Incisional hernia incidence in between the groups was within the global range of incisional hernia incidence among abdominal organ transplant patients, with a higher incidence among liver transplant patients. All factors associated with incisional hernia, such as SSI, DM, and old age, didn't show significance as predictors to incisional hernia formation among the samples.
器官移植术后切口疝会增加发病率，并影响接受腹部器官移植患者的生活质量。目的：估计肝移植和肾移植患者切口疝的发病率以及与切口疝相关的因素。方法：这是一项回顾性队列研究，纳入了2015年至2020年所有接受肝移植和/或肾移植且符合纳入标准的患者。结果：共纳入424例接受移植手术的患者。其中，287例（67.6%）接受了肾移植，132例（31.1%）接受了肝移植。此外，5例（1.1%）接受了肝肾联合移植。所有样本中有14例（3.3%）发生了切口疝。与肾移植患者相比，肝移植患者的发病率更高（肝移植组为6.81%，肾移植组为1.7%），两组之间具有统计学意义（P值=0.007）。多因素分析显示，手术部位感染（SSI）、供体类型、急性器官排斥反应、霉酚酸酯（MMF）和糖尿病均不是患者切口疝的预测因素。结论：各研究组之间的切口疝发病率在腹部器官移植患者全球切口疝发病率范围内，肝移植患者发病率更高。所有与切口疝相关的因素，如SSI、糖尿病和高龄，在样本中均未显示出作为切口疝形成预测因素的显著性。
