RTI International, Seattle, Washington, USA.
Department of Health Metrics Sciences, University of Washington, Seattle, Washington, USA.
Clin Infect Dis. 2021 Dec 15;73(Suppl_5):S374-S381. doi: 10.1093/cid/ciab851.
Minimally invasive tissue sampling (MITS) is increasingly being used to better understand causes of death in low-resource settings. Undernutrition (eg, wasting, stunting) is prevalent among children globally and yet not consistently coded or uniformly included on death certificates in MITS studies when present. Consistent and accurate attribution of undernutrition is fundamental to understanding its contribution to child deaths. In May 2020, members of the MITS Alliance Cause of Death Technical Working Group convened a panel of experts in public health, child health, nutrition, infectious diseases, and MITS to develop guidance for systematic integration of undernutrition, as assessed by anthropometry, in cause of death coding, including as part of the causal chain or as a contributing condition, in children <5 years of age. The guidance presented here will support MITS and other researchers, public health practitioners, and clinicians with a systematic approach to assigning and interpreting undernutrition in death certification.
微创组织采样 (MITS) 越来越多地被用于更好地了解资源匮乏环境下的死亡原因。在全球范围内，儿童普遍存在营养不足（例如消瘦、发育迟缓）的问题，但在 MITS 研究中，当存在营养不足的情况时，却没有一致地进行编码或统一列入死亡证明。一致和准确地归因于营养不足是理解其对儿童死亡的贡献的基础。2020 年 5 月，MITS 联盟死因技术工作组的成员召集了一个公共卫生、儿童健康、营养、传染病和 MITS 方面的专家小组，制定了关于系统地将通过人体测量法评估的营养不足纳入死因编码的指南，包括将其作为因果关系链的一部分或作为促成因素纳入 5 岁以下儿童的死因编码。本指南将为 MITS 和其他研究人员、公共卫生从业者和临床医生提供一种系统的方法，用于在死亡证明中分配和解释营养不足。
