School of Medicine, University of California, San Francisco, San Francisco, California, USA.
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, USA.
J Neuroimaging. 2022 Mar;32(2):253-263. doi: 10.1111/jon.12955. Epub 2021 Dec 15.
Pulsatile tinnitus (PT) is the subjective sensation of a pulse-synchronous sound, most often due to a cerebrovascular etiology. PT can severely impact quality of life and may indicate a life-threatening process, yet a timely and accurate diagnosis can often lead to effective treatment. Clinical assessment with a history and physical examination can often suggest a diagnosis for PT, but is rarely definitive. Therefore, PT should be evaluated with a comprehensive and targeted radiographic imaging protocol. MR imaging provides a safe and effective means to evaluate PT. Specific MR sequences may be used to highlight different elements of cerebrovascular anatomy and physiology. However, routine MR evaluation of PT must comply with economic and practical constraints, while effectively capturing both common and rarer, life-threatening etiologies of PT.
In this state-of-the-art review, we describe our institutional MR protocol for evaluating PT.
This protocol includes the following dedicated sequences: time-of-flight magnetic resonance angiography; arterial spin labeling; spoiled gradient recalled acquisition in the steady state; time-resolved imaging of contrast kinetics; diffusion weighted imaging, and 3-dimensional fluid-attenuated inversion recovery.
We describe the physiologic and clinical rationale for including each MR sequence in a comprehensive PT imaging protocol, and detail the role of MR within the broader evaluation of PT, from clinical presentation to treatment.
脉动性耳鸣(PT)是一种与脉搏同步的主观声音感觉,通常是由于脑血管病因引起的。PT 会严重影响生活质量,并且可能表明存在危及生命的过程,但及时、准确的诊断通常可以导致有效的治疗。通过病史和体格检查进行临床评估通常可以提示 PT 的诊断,但很少能明确诊断。因此,应采用全面且有针对性的影像学成像方案来评估 PT。磁共振成像(MR)为评估 PT 提供了一种安全、有效的手段。特定的 MR 序列可用于突出脑血管解剖和生理学的不同元素。然而,PT 的常规 MR 评估必须符合经济和实际的限制,同时有效地捕捉到 PT 的常见和更罕见的、危及生命的病因。
在这篇最新综述中,我们描述了我们机构用于评估 PT 的 MR 协议。
该协议包括以下专用序列:时间飞越磁共振血管造影;动脉自旋标记;稳态扰相梯度回波;对比动力学的时间分辨成像;弥散加权成像和 3 维液体衰减反转恢复。
我们描述了在全面的 PT 成像方案中纳入每个 MR 序列的生理和临床原理,并详细说明了 MR 在从临床表现到治疗的更广泛的 PT 评估中的作用。