Chen Jianquan, Xuan Tianhang, Lu Yao, Lin Xinyuan, Lv Zhouming, Chen Maoshui
Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Department of Orthopaedics, Guang Dong Province Hospital of Traditional Chinese Medicine Zhuhai Branch, Zhuhai, Guangdong, China.
J Orthop Surg (Hong Kong). 2021 Sep-Dec;29(3):23094990211065579. doi: 10.1177/23094990211065579.
This study assessed the therapeutic effect of one-stage percutaneous endoscopic debridement and lavage (PEDL) combined with percutaneous pedicle screw fixation (PPSF) in the treatment of lumbar pyogenic spondylodiscitis.
From March 2017 to October 2019, 51 patients diagnosed with pyogenic spondylodiscitis underwent PPSF followed by PEDL in our department. Biopsy specimens were examined for microorganisms and evaluated histopathologically. Clinical outcomes were assessed by physical examination, routine serological testing, visual analogue scale (VAS), Oswestry Disability Index (ODI) and imaging studies.
Of the enrolled patients, the operation time ranged from 90 min to 114 min every level with an average of 102 min, and the average drainage time ranged from 6 days to 10 days with an average of 7.4 days. All patients who complained of lower back pain symptoms were more relieved than before surgery. Causative pathogens were identified in 20 of 51 biopsy specimens; was the most prevalent. However, there were eight patients with postoperative complications. The mean follow-up was 25.0 ± 3.8 (range: 20-32) months. Inflammatory markers showed that infection was controlled. The VAS and ODI improved significantly. At the last follow-up, magnetic resonance imaging showed that the infected lesions had disappeared.
PEDL supplementing PPSF may be useful for patients with single-level lumbar pyogenic spondylodiscitis, as it is minimally invasive, especially for patients who cannot undergo conventional open surgery due to poor health or advanced age.
本研究评估了一期经皮内镜清创灌洗术(PEDL)联合经皮椎弓根螺钉内固定术(PPSF)治疗腰椎化脓性脊柱炎的疗效。
2017年3月至2019年10月,我科51例诊断为化脓性脊柱炎的患者接受了PPSF,随后进行了PEDL。对活检标本进行微生物检查并进行组织病理学评估。通过体格检查、常规血清学检测、视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)和影像学检查评估临床疗效。
入选患者中,每个节段手术时间为90分钟至114分钟,平均102分钟,平均引流时间为6天至10天,平均7.4天。所有主诉下腰痛症状的患者均比术前缓解更明显。51份活检标本中有20份鉴定出致病病原体; 最为常见。然而,有8例患者出现术后并发症。平均随访时间为25.0±3.8(范围:20 - 32)个月。炎症指标显示感染得到控制。VAS和ODI显著改善。末次随访时,磁共振成像显示感染病灶已消失。
PEDL辅助PPSF可能对单节段腰椎化脓性脊柱炎患者有用,因为它微创,尤其适用于因健康状况差或年龄较大而无法接受传统开放手术的患者。