Griffith-Jones William, Nasto Luigi Aurelio, Pola Enrico, Stokes Oliver M, Mehdian Hossein
Exeter Spinal Unit, Princess Elizabeth Orthopaedic Centre, Royal Devon & Exeter NHS Foundation Trust, Barrack Road, Exeter, Devon, UK.
The Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospitals, Derby Road, Nottingham, NG7 2UH, UK.
J Orthop Traumatol. 2018 Aug 20;19(1):10. doi: 10.1186/s10195-018-0496-9.
The primary management of pyogenic spondylodiscitis is conservative. Once the causative organism has been identified, by blood culture or biopsy, administration of appropriate intravenous antibiotics is started. Occasionally patients do not respond to antibiotics and surgical irrigation and debridement is needed. The treatment of these cases is challenging and controversial. Furthermore, many affected patients have significant comorbidities often precluding more extensive surgical intervention. The aim of this study is to describe early results of a novel, minimally invasive percutaneous technique for disc irrigation and debridement in pyogenic spondylodiscitis.
A series of 10 consecutive patients diagnosed with pyogenic spondylodiscitis received percutaneous disc irrigation and debridement. The procedure was performed by inserting two Jamshidi needles percutaneously into the disc space. Indications for surgery were poor response to antibiotic therapy (8 patients) and the need for more extensive biopsy (2 patients). Pre- and postoperative white blood cell count (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), Oswestry disability index (ODI), and visual analogue score (VAS) for back pain were collected. Minimum follow-up was 18 months, with regular interval assessments.
There were 7 males and 3 females with a mean age of 67 years. The mean WBC before surgery was 14.63 × 10/L (10.9-26.4) and dropped to 7.48 × 10/L (5.6-9.8) after surgery. The mean preoperative CRP was 188 mg/L (111-250) and decreased to 13.83 mg/L (5-21) after surgery. Similar improvements were seen with ESR. All patients reported significant improvements in ODI and VAS scores after surgery. The average hospital stay after surgery was 8.17 days. All patients had resolution of the infection, and there were no complications associated with the procedure.
Our study confirms the feasibility and safety of our percutaneous technique for irrigation and debridement of pyogenic spondylodiscitis. Percutaneous irrigation and suction offers a truly minimally invasive option for managing recalcitrant spondylodiscitis or for diagnostic purposes. The approach used is very similar to discography and can be easily adapted to different hospital settings.
Level III.
化脓性脊椎椎间盘炎的主要治疗方法是保守治疗。一旦通过血培养或活检确定了病原体,就开始静脉注射适当的抗生素。偶尔,患者对抗生素无反应,需要进行手术冲洗和清创。这些病例的治疗具有挑战性且存在争议。此外,许多受影响的患者有严重的合并症,常常排除了更广泛的手术干预。本研究的目的是描述一种用于化脓性脊椎椎间盘炎椎间盘冲洗和清创的新型微创经皮技术的早期结果。
连续10例被诊断为化脓性脊椎椎间盘炎的患者接受了经皮椎间盘冲洗和清创。该手术通过经皮将两根Jamshidi针插入椎间盘间隙进行。手术指征为对抗生素治疗反应不佳(8例患者)和需要进行更广泛的活检(2例患者)。收集术前和术后的白细胞计数(WBC)、C反应蛋白(CRP)、红细胞沉降率(ESR)、Oswestry功能障碍指数(ODI)以及背痛的视觉模拟评分(VAS)。最短随访时间为18个月,定期进行评估。
男性7例,女性3例,平均年龄67岁。术前平均白细胞计数为14.63×10/L(10.9 - 26.4),术后降至7.48×10/L(5.6 - 9.8)。术前平均CRP为188mg/L(111 - 250),术后降至13.83mg/L(5 - 21)。ESR也有类似改善。所有患者术后ODI和VAS评分均有显著改善。术后平均住院时间为8.17天。所有患者感染均得到解决,且未出现与手术相关的并发症。
我们的研究证实了我们用于化脓性脊椎椎间盘炎冲洗和清创的经皮技术的可行性和安全性。经皮冲洗和抽吸为治疗顽固性脊椎椎间盘炎或用于诊断目的提供了一种真正微创的选择。所采用的方法与椎间盘造影非常相似,并且可以很容易地适应不同的医院环境。
三级。