Western Honduras Gastric Cancer Prevention Initiative, Hospital de Occidente, Santa Rosa de Copán, Honduras.
Universidad Nacional Autónoma de Honduras, School of Medicine, Honduras.
JCO Glob Oncol. 2021 Dec;7:1694-1702. doi: 10.1200/GO.21.00273.
Population-based cancer registries (PBCRs) are critical for national cancer control planning, yet few low- and middle-income countries (LMICs) have quality PBCRs. The Central America Four region represents the principal LMIC region in the Western hemisphere. We describe the establishment of a PBCR in rural Western Honduras with first estimates for the 2013-2017 period.
The Western Honduras PBCR was established through a collaboration of academic institutions and the Honduras Ministry of Health for collection of incident cancer data from public and private health services. Data were recorded using the Research Electronic Data Capture (REDCap) web-based platform with data monitoring and quality checks. Crude and age-standardized rates (ASRs) were calculated at the regional level, following WHO methodology.
The web-based platform for data collection, available ancillary data services (eg, endoscopy), and technical support from international centers (United States and Colombia) were instrumental for quality control. Crude cancer incidence rates were 112.2, 69.8, and 154.6 per 100,000 habitants overall, males, and females, respectively (excluding nonmelanoma skin cancer). The adjusted ASRs were 84.2, 49.6, and 118.9 per 100,000 overall habitants, males, and females, respectively. The most common sites among men were stomach (ASR 26.0, 52.4%), colorectal (ASR 5.11, 10.15%), and prostate (ASR 2.7, 5.4%). The most common sites in women were cervix (ASR 34.2, 36.7%), breast (ASR 11.2, 12.3%), and stomach (ASR 10.8, 11.7%).
The Copán-PBCR represents a successful model to develop cancer monitoring in rural LMICs. Innovations included the use of the REDCap platform and leverage of Health Ministry resources. This provides the first PBCR data for Honduras and the Central America Four and confirms that infection-driven cancers, such as gastric and cervical, should be priority targets for cancer control initiatives.
基于人群的癌症登记处（PBCR）对于国家癌症控制规划至关重要，但很少有低收入和中等收入国家（LMIC）拥有高质量的 PBCR。中美洲四地区代表西半球主要的 LMIC 地区。我们描述了在洪都拉斯西部农村建立一个 PBCR，并对 2013-2017 年期间的首个估计进行了描述。
西部洪都拉斯 PBCR 是通过学术机构与洪都拉斯卫生部的合作建立的，用于从公共和私人卫生服务机构收集癌症发病数据。数据使用基于研究的电子数据捕获（REDCap）网络平台进行记录，并进行数据监测和质量检查。按照世界卫生组织的方法，在区域一级计算了粗率和年龄标准化率（ASR）。
网络数据收集平台、可提供的辅助数据服务（如内窥镜检查）以及来自国际中心（美国和哥伦比亚）的技术支持对于质量控制至关重要。总体、男性和女性的粗癌症发病率分别为每 100,000 居民 112.2、69.8 和 154.6 例（不包括非黑色素瘤皮肤癌）。调整后的 ASR 分别为每 100,000 居民、男性和女性总体为 84.2、49.6 和 118.9 例。男性中最常见的部位是胃（ASR 26.0，52.4%）、结直肠（ASR 5.11，10.15%）和前列腺（ASR 2.7，5.4%）。女性中最常见的部位是子宫颈（ASR 34.2，36.7%）、乳房（ASR 11.2，12.3%）和胃（ASR 10.8，11.7%）。
Copán-PBCR 是在农村低收入和中等收入国家发展癌症监测的成功模式。创新之处包括使用 REDCap 平台和利用卫生部资源。这为洪都拉斯和中美洲四地区提供了首个 PBCR 数据，并证实了感染驱动的癌症（如胃癌和宫颈癌）应成为癌症控制倡议的优先目标。
