Shahesmaeili Armita, Malekpour Afshar Reza, Sadeghi Azadeh, Bazrafshan Azam
Department of Epidemiology and Biostatistics, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran. Email:
Asian Pac J Cancer Prev. 2018 Jun 25;19(6):1533-1541. doi: 10.22034/APJCP.2018.19.6.1533.
Introduction: The epidemiology of common cancers in Kerman province, southeast of Iran, was assessed based upon results of the Kerman Population-Based Cancer Registry Program (KPBCR). Methods: in this retrospective study, all patients diagnosed with primary cancers and registered with the KPBCR were included. New cancer cases registered from 2014 were identified from pathological labs, medical reports of 48 health facilities providing cancer diagnosis or treatment services and the national death registry program. Data for patients who were referred to neighboring provinces to access health services were also collected from national referral registries. Results from autopsies was additionally extracted from regional forensic and legal medicine centers and added to the registry periodically. Age standardized incidence rates (ASRs) per 100,000 person-years for all cancers were computed, using direct-standardization and CanReg methodology. Mortality to incidence (M:I) ratios and microscopically verified (MV) proportions were calculated as quality measures. Results: A total of 2,838 cases of cancer were registered in Kerman province, 2014. Of these 45. 6% involved women (n=1,293). Individuals aged 60-64 years represented the largest proportion (11.6%) of the total cancer prevalence, followed by those aged 55-59 years (10.86%) and 65-69 years (8.99%). The ASRs for all cancers were 155.1 and 118.90 per 100,000, in men and women, respectively. In women, breast (ASR: 26.4), skin (ASR: 13.0), thyroid (ASR: 9.2), leukemia (ASR: 8.0) and colorectal (ASR: 7.70) were the most common cancers. In men, bladder (ASR: 24.70), skin (ASR: 16.80), lung (ASR: 14.6), leukemia (ASR: 14.50), and stomach (ASR: 10.8) were found to be the most frequent. Conclusion: This study provided latest evidence on epidemiology of cancer in the southeast of Iran that could be used to empower prevention and control interventions in a developing country.
基于克尔曼省人群癌症登记项目(KPBCR)的结果,对伊朗东南部克尔曼省常见癌症的流行病学情况进行了评估。方法:在这项回顾性研究中,纳入了所有被诊断为原发性癌症并在KPBCR登记的患者。2014年起登记的新癌症病例来自病理实验室、48家提供癌症诊断或治疗服务的医疗机构的医疗报告以及国家死亡登记项目。转诊至邻省获取医疗服务的患者数据也从国家转诊登记处收集。尸检结果还从地区法医和法医学中心提取,并定期添加到登记册中。使用直接标准化和CanReg方法计算了所有癌症每10万人年的年龄标准化发病率(ASR)。计算了死亡率与发病率(M:I)之比和显微镜确诊(MV)比例作为质量指标。结果:2014年克尔曼省共登记了2838例癌症病例。其中45.6%为女性(n = 1293)。60 - 64岁的个体在癌症总患病率中占比最大(11.6%),其次是55 - 59岁的个体(10.86%)和65 - 69岁的个体(8.99%)。所有癌症的ASR在男性和女性中分别为每10万人155.1和118.90。在女性中,乳腺癌(ASR:26.4)、皮肤癌(ASR:13.0)、甲状腺癌(ASR:9.2)、白血病(ASR:8.0)和结直肠癌(ASR:7.70)是最常见的癌症。在男性中,膀胱癌(ASR:24.70)、皮肤癌(ASR:16.80)、肺癌(ASR:14.6)、白血病(ASR:14.50)和胃癌(ASR:10.8)是最常见的。结论:本研究提供了伊朗东南部癌症流行病学的最新证据,可用于加强发展中国家的预防和控制干预措施。